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公开(公告)号：EP1945670A2
公开(公告)日：2008-07-23
申请号：EP06794995.8
申请日：2006-10-18
CPC分类号： C07K16/28 , A61K39/3955 , A61K39/39558 , C07K16/2869 , C07K2317/56 , C07K2317/569 , C07K2317/76
摘要： The present invention relates to agents which modulate the effect of a RAMP (Receptor Activity MoifyingProtein) protein on a Calcitonin Receptor Like Receptor (CRLR). Also included in the present invention are methods and uses of such agents and assays for identifying such agents. The agents of the present disclosure may be used in the treatment of, for example, cancer, obesity and other disorders.
摘要翻译： 本发明涉及调节RAMP（受体活性MoisingProtein）蛋白质对降钙素受体样受体（CRLR）的作用的药剂。 本发明还包括用于鉴定这些药剂的这些药剂和测定法的方法和用途。 本公开的药剂可用于治疗例如癌症，肥胖症和其他病症。
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公开(公告)号：EP2152753B1
公开(公告)日：2012-08-08
申请号：EP08750480.9
申请日：2008-04-23
CPC分类号： C07K16/30 , A61K39/39558 , A61K45/06 , A61K2039/505 , C07K16/2869 , C07K16/3015 , C07K16/3046 , C07K16/3053 , C07K16/3069 , C07K2317/73 , C07K2317/74 , C07K2317/76
摘要： The present invention provides an isolated antibody capable of binding a receptor activity modifying protein (RAMP) of CRLR receptor which antibody is of IgG, IgA or IgM isotype.
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公开(公告)号：EP2402372A3
公开(公告)日：2012-05-02
申请号：EP11162714.7
申请日：2006-10-18
IPC分类号： C07K16/28 , C12N15/13 , A61K39/395 , C12Q1/68 , G01N33/53 , A61P3/04 , A61P19/02 , A61P35/00 , A61P19/10 , A61P9/04 , A61P29/00 , A61P9/00
CPC分类号： C07K16/28 , A61K39/3955 , A61K39/39558 , C07K16/2869 , C07K2317/56 , C07K2317/569 , C07K2317/76
摘要： The present invention relates to agents which modulate the effect of a RAMP (Receptor Activity Modifying Protein) protein on a Calcitonin Receptor Like Receptor (CRLR). Also included in the present invention are methods and uses of such agents and assays for identifying such agents. The agents of the present disclosure may be used in the treatment of, for example, cancer, obesity and other disorders.
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公开(公告)号：EP2402372A2
公开(公告)日：2012-01-04
申请号：EP11162714.7
申请日：2006-10-18
IPC分类号： C07K16/28 , C12N15/13 , A61K39/395 , C12Q1/68 , G01N33/53 , A61P3/04 , A61P19/02 , A61P35/00 , A61P19/10 , A61P9/04 , A61P29/00 , A61P9/00
CPC分类号： C07K16/28 , A61K39/3955 , A61K39/39558 , C07K16/2869 , C07K2317/56 , C07K2317/569 , C07K2317/76
摘要： The present invention relates to agents which modulate the effect of a RAMP (Receptor Activity Modifying Protein) protein on a Calcitonin Receptor Like Receptor (CRLR). Also included in the present invention are methods and uses of such agents and assays for identifying such agents. The agents of the present disclosure may be used in the treatment of, for example, cancer, obesity and other disorders.
摘要翻译： 本发明涉及调节RAMP（受体活性修饰蛋白）蛋白对降钙素受体相似受体（CRLR）的作用的试剂。 本发明还包括这些试剂的方法和用途以及用于鉴定这些试剂的测定法。 本公开的药剂可用于治疗例如癌症，肥胖症和其它疾病。
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公开(公告)号：EP2152753A1
公开(公告)日：2010-02-17
申请号：EP08750480.9
申请日：2008-04-23
CPC分类号： C07K16/30 , A61K39/39558 , A61K45/06 , A61K2039/505 , C07K16/2869 , C07K16/3015 , C07K16/3046 , C07K16/3053 , C07K16/3069 , C07K2317/73 , C07K2317/74 , C07K2317/76
摘要： The present invention provides an isolated antibody capable of binding a receptor activity modifying protein (RAMP) of CRLR receptor which antibody is of IgG, IgA or IgM isotype.
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