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1.发明授权
公开(公告)号：EP1996214B1
公开(公告)日：2016-05-04
申请号：EP07750725.9
申请日：2007-02-13
申请人： University of Iowa Research Foundation , The Trustees of Columbia University in the City of New York , National Institutes of Health, DHHS
IPC分类号： C12Q1/68
CPC分类号： A61K38/1709
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公开(公告)号：EP1360189A1
公开(公告)日：2003-11-12
申请号：EP02718868.9
申请日：2002-01-25
CPC分类号： C07K5/0827 , A61K38/00 , C07F5/025 , C07F5/04 , C07K5/06191 , C07K7/02
摘要： The invention relates to the formulation of pharmaceutical compounds. More particularly, the invention provides stable, pharmaceutically acceptable compositions prepared from boronic acid compounds and methods for preparing the compositions. The invention also provides novel boronate ester compounds. The invention further provides boronic acid anhydride compounds useful in the methods of the invention.
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3.发明授权IMMUNOGENIC COMPOSITIONS CONTAINING ANTHRAX ANTIGEN, BIODEGRADABLE POLYMER MICROPARTICLES, AND POLYNUCLEOTIDE-CONTAINING IMMUNOLOGICAL ADJUVANT 有权免疫原性组合物，炭疽抗原的微粒由生物可降解聚合物，以及甲佐剂NUKLEINSÄUREHÄLTIGESINCLUDE。
公开(公告)号：EP1812056B1
公开(公告)日：2013-08-07
申请号：EP05858489.7
申请日：2005-11-15
发明人： O'HAGAN, Derek,T. , SINGH, Manmohan, c/o Novartis Vaccines and Diagnostics, Inc. , KLINMAN, Dennis, M.
IPC分类号： A61K39/07
CPC分类号： A61K9/0019 , A61K9/1647 , A61K9/167 , A61K39/00 , A61K39/07 , A61K2039/55555 , A61K2039/55561
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公开(公告)号：EP1996214A2
公开(公告)日：2008-12-03
申请号：EP07750725.9
申请日：2007-02-13
申请人： University of Iowa Research Foundation , The Trustees of Columbia University in the City of New York , National Institutes of Health, DHHS
IPC分类号： A61K38/00
CPC分类号： A61K38/1709
摘要： Methods for identifying a subject at risk for developing AMD are disclosed. The methods include identifying specific protective or risk polymorphisms or genotypes from the subject's genetic material. Therapeutic compositions and methods are also provided for delaying the progression or onset of the development of AMD in a subject, including treating a subject having signs and/or symptoms of AMD or who has been diagnosed with AMD.
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5.发明公开IMMUNOGENIC COMPOSITIONS CONTAINING ANTHRAX ANTIGEN, BIODEGRADABLE POLYMER MICROPARTICLES, AND POLYNUCLEOTIDE-CONTAINING IMMUNOLOGICAL ADJUVANT 有权免疫原性组合物，炭疽抗原的微粒由生物可降解聚合物，以及甲佐剂NUKLEINSÄUREHÄLTIGESINCLUDE。
公开(公告)号：EP1812056A2
公开(公告)日：2007-08-01
申请号：EP05858489.7
申请日：2005-11-15
IPC分类号： A61K39/07
CPC分类号： A61K9/0019 , A61K9/1647 , A61K9/167 , A61K39/00 , A61K39/07 , A61K2039/55555 , A61K2039/55561
摘要： Immunogenic compositions and kits, as well as methods of stimulating immune responses and methods of immunization using the same. The compositions and kits comprise: (a) an antigen derived from Bacillus anthracis; (b) polymer microparticles comprising a biodegradable polymer; and (c) a polynucleotide-containing immunological adjuvant.
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