-
公开(公告)号：EP2534949A4
公开(公告)日：2013-11-20
申请号：EP11739922
申请日：2011-02-08
发明人： KOBAYAKAWA KO , KOBAYAKAWA REIKO
IPC分类号： A01N31/02 , A01N43/02 , A01N43/10 , A01N43/36 , A01N43/78 , A01N43/84 , A01N47/46 , A01P17/00
摘要： The present invention provides an animal repellent comprising, as an active ingredient, a compound having an odor innately inducing fear in animals, which is free from acclimation of animals to the aforementioned odor. The present invention relates to animal repellent comprising, as an active ingredient, at least one kind selected from a heterocyclic compound represented by the formula (1) : wherein ring A is a 3- to 7-membered heterocycle containing at least one hetero atom selected from a nitrogen atom, a sulfur atom and an oxygen atom, and R 1 and R 2 are each independently hydrogen, a halogen atom, an optionally substituted alkyl group, an optionally substituted alkoxy group, an acyl group, an optionally esterified carboxyl group, an optionally substituted thiol group, an optionally substituted amino group or an oxo group, or a salt thereof, a chain sulfide compound and alkyl isothiocyanate.
-
公开(公告)号：EP0842948A4
公开(公告)日：2004-12-15
申请号：EP96921136
申请日：1996-07-01
IPC分类号： A61K38/00 , C07K16/28 , C07K16/18 , A61K39/395 , C12N5/20 , C12N15/06 , C12P21/08 , C12R1/91 , G01N33/53 , G01N33/577
CPC分类号： C07K16/2875 , A61K38/00 , C07K2317/24 , C07K2317/34 , C07K2319/00
摘要： A method for assaying, in particular, Fas ligands in a human bodily fluid by using an antiFas ligand antibody, the antibody to be used in this method, an assay reagent, an assay kit; an antiFas ligand antibody capable of highly (for example, at a ratio of 50 % or above) inhibiting apoptosis due to Fas ligands and the antiFas ligand antibody which is a humanized antibody; a hybridoma or a cell line which produces the antibody; a composition or drug which comprises as an essential component or the active ingredient at least one of the antiFas ligand antibodies; and a method for treating systemic or topical morbid conditions or diseases which are accompanied by abnormalities in the Fas antigen/Fas ligand system or in the apoptosis mediated by the Fas antigen, or induced by such abnormalities, or in which such abnormalities participate, which method comprises administering to a patient a therapeutically effective amount of the antiFas ligand antibody capable of inhibiting the apoptosis of cells in which Fas antigen expressed by the Fas ligand.
-
公开(公告)号：EP1111387A4
公开(公告)日：2002-08-21
申请号：EP99940663
申请日：1999-09-03
发明人： ODA HIROSHI , SEIKI KOSUKE , NAKAJIMA HIROSHI , SATO NOBUYUKI , URADE YOSHIHIRO T , HIRAWA NOBUHITO , UEHARA YOSHIO
CPC分类号： G01N33/6893 , G01N33/573 , G01N33/70 , G01N33/88 , G01N2800/347 , Y10S436/811
摘要： A method for detecting kidney diseases at the early stage characterized by measuring the concentration of human lipocalin-type prostaglandin D synthase in a body fluid sample collected from a subject and comparing the thus measured concentration with the human lipocalin-type prostaglandin D synthase concentration of body fluid samples obtained from healthy subjects; and a method for pathologically controlling kidney diseases characterized by measuring the concentration of human lipocalin-type prostaglandin D synthase in a body fluid sample collected from a subject and evaluating the glomerular filtration level of the patient therefrom.
-
公开(公告)号：EP0992243A4
公开(公告)日：2000-04-12
申请号：EP97909714
申请日：1997-10-31
发明人： NAGATA SHIGEKAZU , YATOMI TAKEHIRO , SUDA TAKASHI
IPC分类号： A61K38/00 , A61P1/16 , A61P9/00 , A61P13/00 , A61P31/00 , A61P37/06 , C07K14/705 , C07K16/28 , A61K39/395 , A01N1/02 , A61K38/18 , A61K45/00
CPC分类号： C07K14/70578 , A61K38/00 , A61K2039/505 , C07K16/2875 , C07K16/2878 , C07K2319/00 , C07K2319/30
摘要： The present invention aims at preventing and treating the diseases wherein involvement of apoptosis has been indicated, and the present invention is directed to a prophylactic/therapeutic agent or a cell apoptosis inhibitory agent or an organ preservative agent containing a Fas antagonist as its effective component.
-
公开(公告)号：EP1059089A4
公开(公告)日：2005-01-19
申请号：EP99902839
申请日：1999-02-05
发明人： YATOMI TAKEHIRO , NAGATA SHIGEKAZU , SUDA TAKASHI
IPC分类号： A61K38/00 , A61P29/00 , C07K16/28 , A61K39/395
CPC分类号： C07K16/2875 , A61K38/00 , A61K2039/505
摘要： Preventives/remedies for at least one disease selected from the group consisting of inflammatory intestinal disease, ischemic colitis and idiopathic inflammatory intestinal disease induced by infection, chemicals and radiation which contain as the active ingredient an anti-Fas ligand antibody; and preventives and remedies with the use of the same.
-
公开(公告)号：EP1208841A4
公开(公告)日：2003-01-15
申请号：EP00950011
申请日：2000-08-04
申请人： TEIJIN LTD , OSAKA BIOSCIENCE INST
发明人： SUWA YORIMASA , YOSHIOKA NOBORU , ARAI TAKAMI , SAKURAI KATSUTOSHI , SUZUKI JUN , WATANABE YASUYOSHI , SUZUKI MASAAKI , SATOH TAKUMI , WATANABE YUMIKO , KATAOKA YOSUKE
IPC分类号： A61K31/5578 , A61P25/28
CPC分类号： A61K31/5575 , A61K31/5578
摘要： Remedies for nerve degeneration diseases containing as the active ingredient (15R)-isocarbacyclin derivatives of general formula [I] or 15-deoxyisocarbacyclin derivatives of general formula [III]. In formula [I] and [III] R1 is C1-C6 alkylene; and R is hydrogen, C1-C7 alkyl, or a protective group.
-
7.发明公开
公开(公告)号：EP1158298A4
公开(公告)日：2002-04-17
申请号：EP00905354
申请日：2000-02-25
发明人： SEIKI KOSUKE , ODA HIROSHI , NAKAJIMA HIROSHI , SATO NOBUYUKI , URADE YOSHIHIRO , UEHARA YOSHIO , INOUE TERUO
IPC分类号： C12Q1/25 , G01N33/573
CPC分类号： C12Q1/25 , G01N33/573 , G01N2333/9015
摘要： A method for presuming restenosis following coronary vessel intervention by measuring human lipocalin-type prostaglandin D synthase (hereinafter referred to as L-PGDS) in a body fluid sample. More particularly, this method comprises measuring the L-PGDS concentration in the sample and presuming restenosis following coronary vessel intervention by using changes therein as an indication.
-
公开(公告)号：EP0913405A4
公开(公告)日：2003-03-05
申请号：EP96935508
申请日：1996-10-31
申请人： MARUHA CORP , OSAKA BIOSCIENCE INST
发明人： ODA HIROSHI , SATO NOBUYUKI , NISHIKAWA MASAZUMI , SEIKI KOSUKE , URADE YOSHIHIRO , SAJI FUMITAKA
IPC分类号： C07K16/40 , C12N15/08 , C12P21/08 , G01N33/536 , G01N33/573
CPC分类号： C07K16/40 , Y10S530/809
摘要： A monoclonal antibody specifically recognizing a cerebral prostaglandin D synthetase; hybridomas producing the monoclonal antibody; a method for detecting a cerebral prostaglandin D synthetase or diseases which comprises detecting the synthetase with the use of the monoclonal antidody; and a kit for detecting a cerebral prostaglandin D synthetase which contains the monoclonal antibody.
-
公开(公告)号：EP0999447A4
公开(公告)日：2002-02-27
申请号：EP98917737
申请日：1998-04-30
申请人： MARUHA CORP , OSAKA BIOSCIENCE INST
发明人： ODA HIROSHI , SATO NOBUYUKI , NISHIKAWA MASAZUMI , SEIKI KOSUKE , URADE YOSHIHIRO , EGUCHI YUTAKA , EGUCHI NAOMI
IPC分类号： G01N33/573 , G01N33/88 , A61B5/00 , A61B5/14
CPC分类号： G01N33/88 , G01N33/573 , Y10S435/81 , Y10S435/975 , Y10S436/805 , Y10S436/811
摘要： A method for detecting or predicting ischemic diseases by using as an indication the concentration of human cerebral prostaglandin D synthetase (hPGDS) in bodily fluid samples. In this method, the hPGDS concentration data of bodily fluid samples taken from subjects are compared with the standard range defined by using normal subjects to thereby detect or predict ischemic diseases.
-
10.发明公开METHOD FOR DETECTING MUSCLE DEGENERATIVE DISEASES, AND METHOD FOR DETERMINING THERAPEUTIC EFFICACY ON THE DISEASES 审中-公开检测方法的疾病MUSKELDEGENERATIVEN和方法，以确定疗效作用，对疾病
公开(公告)号：EP2407784A4
公开(公告)日：2012-09-05
申请号：EP10750778
申请日：2010-03-08
发明人： URADE YOSHIHIRO , ARITAKE KOSUKE , MARUYAMA TOSHIHIKO , KAMAUCHI SHINYA , TAKEDA SHIN ICHI , NAKAMURA AKINORI
IPC分类号： G01N33/53 , C07K16/44 , G01N27/62 , G01N30/72 , G01N30/88 , G01N33/15 , G01N33/50 , G01N33/68
CPC分类号： G01N33/6893 , G01N30/7233 , G01N2030/8813 , G01N2800/28 , G01N2800/2878
-
-
-
-
-
-
-
-
-
搜索结果
16 条记录 (耗时 0.01 秒)
