公开(公告)号：EP2906232A1

公开(公告)日：2015-08-19

申请号：EP13847671.8

申请日：2013-10-15

申请人： Pittenger, Mark Frings ,  Sanchez, Pablo Gerardo

发明人： Pittenger, Mark Frings ,  Sanchez, Pablo Gerardo

IPC分类号： A61K35/42

CPC分类号： A01N1/0247 ,  A01N1/0226 ,  A61K35/28 ,  A61K38/18 ,  A61K38/1833 ,  A61K38/1891 ,  A61K38/193 ,  A61K38/196 ,  A61K38/2066

摘要： This application describes an apparatus and a method for the treatment of a damaged lung, heart, or other organ or tissue using cells contained in the apparatus and a liquid interface that allows communication with the circulation of the damaged organ or tissue. The apparatus can be used to treat the organ inside or outside the body. The apparatus is designed to sit outside the body but a similar apparatus is envisioned that is implantable. The apparatus contains a porous material or matrix that the cells are grown on, and the volume of the apparatus provides that it can contain a therapeutically useful number of cells in the range 0.5×10e6 to 200×10e6.

公开(公告)号：EP2906232A4

公开(公告)日：2016-09-28

申请号：EP13847671

申请日：2013-10-15

申请人： PITTENGER MARK FRINGS ,  SANCHEZ PABLO GERARDO

发明人： PITTENGER MARK FRINGS ,  SANCHEZ PABLO GERARDO

IPC分类号： A61K35/42

CPC分类号： A01N1/0247 ,  A01N1/0226 ,  A61K35/28 ,  A61K38/18 ,  A61K38/1833 ,  A61K38/1891 ,  A61K38/193 ,  A61K38/196 ,  A61K38/2066

摘要： This application describes an apparatus and a method for the treatment of a damaged lung, heart, or other organ or tissue using cells contained in the apparatus and a liquid interface that allows communication with the circulation of the damaged organ or tissue. The apparatus can be used to treat the organ inside or outside the body. The apparatus is designed to sit outside the body but a similar apparatus is envisioned that is implantable. The apparatus contains a porous material or matrix that the cells are grown on, and the volume of the apparatus provides that it can contain a therapeutically useful number of cells in the range 0.5×10e6 to 200×10e6.

摘要翻译： 本申请描述了使用装置中包含的细胞和允许与损伤的器官或组织的循环连通的液体界面来治疗损伤的肺，心脏或其他器官或组织的装置和方法。 该装置可用于在体内或体外处理器官。 该设备被设计成坐在身体外部，但是可以设想到可植入的类似装置。 该装置包含细胞在其上生长的多孔材料或基质，并且该装置的体积使得其可以含有0.5×10e6至200×10e6范围内的治疗有用数量的细胞。