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1.发明公开
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公开(公告)号：EP3900658A1
公开(公告)日：2021-10-27
申请号：EP20749064.0
申请日：2020-01-30
发明人： WANG, Jie
摘要： A radio frequency generator for ablation, configured to deliver a direct current, an alternating current, and a radio frequency energy to a lesion for treating a pulmonary disease. The radio frequency generator for ablation can determine the ablation effectiveness according to one or more of a falling value of impedance, a change rate of impedance, the change in the change rate of impedance, or the change of impedance from falling to rising. According to the radio frequency generator for ablation, a segmentation control method and dynamic smoothing are used for adjusting a radio frequency output power to control an ablation temperature, and a tissue to be ablated is avoided being quickly heated in short time to ensure the smooth change in the radio frequency output power in the ablation process. The radio frequency generator for ablation further comprises a specific protection mechanism for preventing repeating ablation. A temperature of a site to be ablated is detected before each ablation is applied. If the temperature of the site to be ablated is higher than 40°C to 60°C, ablation is not started. Also disclosed is a multi-electrode ablation device including the radio frequency generator for ablation.
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3.发明公开
公开(公告)号：EP3383303A1
公开(公告)日：2018-10-10
申请号：EP16870095.3
申请日：2016-12-01
发明人： WANG, Jie
CPC分类号： A61B18/14 , A61B18/1492 , A61N1/056 , A61N1/36117
摘要： Disclosed herein are system and method for locating and identifying nerves innervating the wall of arteries such as the renal artery. The system identifies area on vessel wall innervated with nerves; provides indication on whether energy is delivered accurately to a targeted nerve; and provides immediate post-procedural assessment of the effect of energy delivered to the nerve. The method includes evaluating a change in physiological parameters after energy is delivered to arterial wall; and determining the type of nerve that the energy was directed to (sympathetic or parasympathetic or none) based on the evaluated results. The system includes at least a device (101) for delivering energy to the wall of blood vessel; sensor (103) for detecting physiological signals from a subject; and indicator (105) to display results obtained using said method. Also provided are catheters (2510, 2520) for performing the mapping and ablating functions.
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公开(公告)号：EP2887900B1
公开(公告)日：2020-12-02
申请号：EP13830265.8
申请日：2013-08-23
发明人： WANG, Jie , LI, Chuwu , ZOU, Bo , WANG, Jiancong
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公开(公告)号：EP3659537A1
公开(公告)日：2020-06-03
申请号：EP19201983.4
申请日：2012-08-24
发明人： WANG, Jie
摘要： System and method for locating and identifying nerves innervating the wall of arteries such as the renal artery are disclosed. The present invention identifies areas on vessel walls that are innervated with nerves; provides indication on whether energy is delivered accurately to a targeted nerve; and provides immediate post-procedural assessment of the effect of energy delivered to the nerve. The method includes at least the steps to evaluate a change in physiological parameters after energy is delivered to an arterial wall; and to determine the type of nerve that the energy was directed to (none, sympathetic or parasympathetic) based on the evaluated results. The system includes at least a device for delivering energy to the wall of blood vessel; sensors for detecting physiological signals from a subject; and indicators to display results obtained using said method. Also provided are catheters for performing the mapping and ablating functions
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