公开(公告)号：EP3310355A1

公开(公告)日：2018-04-25

申请号：EP16734519.8

申请日：2016-06-16

申请人： Lazo, John S. ,  Sharlow, Elizabeth R. ,  McQueeney, Kelley E. ,  Wipf, Peter ,  Salamoun, Joseph M.

发明人： Lazo, John S. ,  Sharlow, Elizabeth R. ,  McQueeney, Kelley E. ,  Wipf, Peter ,  Salamoun, Joseph M.

IPC分类号： A61K31/4365 ,  C07D403/00 ,  A61P35/00

摘要： The invention provides protein tyrosine phosphatase inhibitor compounds, Their pharmaceutical compositions, uses, and methods of use, such as in the treatment of various cancers, and process for making the compounds. Also disclosed is an improved synthesis of protein tyrosine phosphatase inhibitor and precursor compound thienopyridone (5).