公开(公告)号：EP4249077A1

公开(公告)日：2023-09-27

申请号：EP21894629.1

申请日：2021-11-16

申请人： Shionogi & Co., Ltd ,  Shionogi Pharma Co., Ltd.

发明人： MAJIMA, Shohei

IPC分类号： A61P43/00 ,  B01J35/02 ,  C07B53/00 ,  C07D219/02 ,  C07D219/04 ,  C07D219/06 ,  C07D219/08 ,  C07F5/02 ,  C07B61/00 ,  C07D498/14 ,  B01J31/02 ,  A61K31/5383

摘要： The present invention provides novel aclidinium salt of the formula (I) and a process for the production of the aclidinium salt.

wherein R 1 is C1-C6 alkyl or C1-C6 alkyloxy; R 2 is hydrogen or C1-C6 alkyloxy; R 3 is hydrogen, halogen, C1-C6 alkyl or C1-C6 alkyloxy; R 4 is hydrogen, C1-C6 alkyloxy, halo C1-C6 alkyloxy or C1-C6 alkylamino; R 5 is C1-C3 alkyl; and X - is an anion.