专利检索 ap:"SignalChem Lifesciences Corporation" 第 1 页

1.

发明公开
COMBINATION THERAPY FOR TREATING BLOOD CANCER 审中-公开

公开(公告)号：EP3852766A1

公开(公告)日：2021-07-28

申请号：EP19780095.6

申请日：2019-09-18

申请人： SignalChem Lifesciences Corporation

发明人： ZHANG, Zaihui , JIANG, Xiaoyan , ROTHE, Katharina , NIU, Xiaojia

IPC分类号： A61K31/635 , A61K31/4545 , A61P35/00 , A61P35/02

2.

发明授权
AMINOPYRIDINE DERIVATIVES AS TAM FAMILY KINASE INHIBITORS 有权

公开(公告)号：EP3074390B1

公开(公告)日：2020-07-08

申请号：EP14819178.6

申请日：2014-11-26

申请人： SignalChem Lifesciences Corporation

发明人： ZHANG, Zaihui

IPC分类号： C07D413/14 , A61K31/506 , A61P35/00

3.

发明公开
ARYL SULFONAMIDE COMPOUNDS AS CARBONIC ANHYDRASE INHIBITORS AND THEIR THERAPEUTIC USE 审中-公开
标题翻译：芳基磺酰胺化合物作为碳酸酐酶抑制剂及其治疗用途

公开(公告)号：EP3317255A1

公开(公告)日：2018-05-09

申请号：EP16738988.1

申请日：2016-07-01

申请人： SignalChem Lifesciences Corporation

发明人： ZHANG, Zaihui

IPC分类号： C07D233/32 , A61K31/4166 , A61P35/00

CPC分类号： C07D233/32 , A61P35/00 , A61P35/04 , C07D401/04 , C07D403/10 , C07D413/10

摘要： Disclosed herein are compounds having the following structure useful as inhibitors of carbonic anhydrase IX (CAIX) and XII, and particularly useful for reducing or eliminating metastases see Formula (I).

4.

发明授权
CARBONIC ANHYDRASE IX-RELATED MARKERS AND USE THEREOF 有权
标题翻译：碳酸酐酶IX相关标记及其用途

公开(公告)号：EP2771488B1

公开(公告)日：2018-03-28

申请号：EP12799669.2

申请日：2012-10-24

申请人： SignalChem Lifesciences Corporation , British Columbia Cancer Agency Branch

发明人： MCDONALD, Paul, C. , LOCK, Frances, E. , DEDHAR, Shoukat

IPC分类号： A61K31/63 , A61K31/337 , A61K31/7048 , G01N33/50 , G01N33/574 , C12Q1/68

CPC分类号： A61K31/337 , A61K31/63 , A61K31/7048 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158 , G01N33/5011 , G01N33/5023 , G01N33/5073 , G01N33/57484 , G01N33/57492

摘要： The present disclosure provides methods for detecting the presence of a cancer stem cell and their use in cancer prognosis, evaluating risk of cancer metastasis, identifying or validating drug candidates, and determining treatment efficacy. It also provides kits useful for detecting the presence of cancer stem cells as well as methods of treating cancer using CAIX inhibitors.

5.

发明公开
USE OF THE AXL INHIBITOR SLC-391 AS ANTIVIRAL THERAPEUTIC AGENT 审中-公开

公开(公告)号：EP4284368A1

公开(公告)日：2023-12-06

申请号：EP22705635.5

申请日：2022-02-01

申请人： SignalChem Lifesciences Corporation

发明人： ZHANG, Zaihui , YAN, Jun , XIE, Zhiwei

IPC分类号： A61K31/4545 , A61P31/12 , A61P31/14 , A61P31/16

6.

发明公开
AMINOPYRIDINE DERIVATIVES AS TAM FAMILY KINASE INHIBITORS 审中-公开
标题翻译：氨基酸衍生物ALS KINASEINHIBITOREN DER TAM-FAMILIE

公开(公告)号：EP3074390A2

公开(公告)日：2016-10-05

申请号：EP14819178.6

申请日：2014-11-26

申请人： SignalChem Lifesciences Corporation

发明人： ZHANG, Zaihui

IPC分类号： C07D413/14 , A61K31/506 , A61P35/00

摘要： Provided herein are aminopyridine derivatives and pharmaceutical compositions that are useful as TAM family kinase inhibitors.

摘要翻译： 本文提供了可用作TAM家族激酶抑制剂的氨基吡啶衍生物和药物组合物。