公开(公告)号：EP4370149A1

公开(公告)日：2024-05-22

申请号：EP22842825.6

申请日：2022-07-13

申请人： The Board of Regents of the University of Oklahoma

发明人： DEANGELIS, Paul, L. ,  GREEN, Dixy, E. ,  WILHELM, Stefan ,  YANG, Wen

IPC分类号： A61K39/00 ,  A61K47/69

CPC分类号： A61K39/39 ,  A61K2039/5555520130101 ,  A61K47/6903 ,  A61K47/60

公开(公告)号：EP4259188A2

公开(公告)日：2023-10-18

申请号：EP21904296.7

申请日：2021-12-08

申请人： The Board of Regents of the University of Oklahoma

发明人： KASUS-JACOBI, Anne ,  PEREIRA, Heloise, Anne ,  STOCK, Amanda, J.

IPC分类号： A61K38/48 ,  C07K14/47 ,  C12N9/48

公开(公告)号：EP4178675A1

公开(公告)日：2023-05-17

申请号：EP21836967.6

申请日：2021-07-08

申请人： Oklahoma Medical Research Foundation ,  The Board of Regents of the University of Oklahoma

发明人： AXTELL, Robert ,  KUMAR, Gaurav ,  AGASING, Agnieshka

IPC分类号： A61P21/00 ,  A61P25/00 ,  A61P25/14 ,  A61P25/28 ,  G01N33/53 ,  G01N33/68

公开(公告)号：EP4000228A1

公开(公告)日：2022-05-25

申请号：EP20840318.8

申请日：2020-06-11

申请人： The Board of Regents of the University of Oklahoma

发明人： IMRAN, Ali ,  FAROOQ, Hasan ,  ASGHAR, Ahmad

IPC分类号： H04L12/911 ,  H04W28/16 ,  G06N7/00

公开(公告)号：EP3965810A1

公开(公告)日：2022-03-16

申请号：EP20805950.1

申请日：2020-05-08

申请人： The Board Of Regents Of The University Of Oklahoma

发明人： BALLARD, Jimmy, D. ,  BLAND, Sarah, J.

IPC分类号： A61K39/08

公开(公告)号：EP3650043A3

公开(公告)日：2020-07-29

申请号：EP19201178.1

申请日：2016-06-07

申请人： The Board of Regents of the University of Oklahoma

发明人： MORTON, Daniel J. ,  SEALE, Thomas W. ,  STULL, Terrence L. ,  WHITBY, Paul W.

IPC分类号： A61K39/102 ,  C07H21/04 ,  C07K14/00 ,  C12P21/04 ,  A61P31/04 ,  C07K14/285

摘要： Immunogenic peptides, fusion polypeptides, and carrier molecules which include the immunogenic peptides, and immunogenic compositions which include these immunogenic peptides, fusion polypeptides, and/or carrier molecules bearing the peptides, and which are able to elicit antibody production against Haemophilus influenzae (Hi), are disclosed. Also disclosed are methods of their use in causing an antibody response against one or more strains of Hi.

公开(公告)号：EP2324336B1

公开(公告)日：2020-03-18

申请号：EP09812118.9

申请日：2009-09-01

申请人： The Board of Regents of the University of Oklahoma

发明人： COMMURI, Sesh

IPC分类号： E01C19/28 ,  G01N29/14 ,  G01N29/26 ,  G01N29/46 ,  G01N9/36

公开(公告)号：EP3419988A1

公开(公告)日：2019-01-02

申请号：EP17757401.9

申请日：2017-02-26

申请人： The Board of Regents of the University of Oklahoma ,  Hill, Alyssa C.

发明人： HILL, Alyssa, C. ,  SCHROEDER, Susan, J.

IPC分类号： C07H21/00 ,  C07H21/02 ,  C12N15/11

公开(公告)号：EP3416635A1

公开(公告)日：2018-12-26

申请号：EP17753700.8

申请日：2017-02-14

申请人： The Board of Regents of the University of Oklahoma

发明人： DU, Lin ,  CICHEWICZ, Robert ,  NICHOLAS, Ken ,  YOU, Jianlan

IPC分类号： A61K31/19 ,  A61K31/215 ,  A61P17/04

CPC分类号： A61K31/215 ,  A61K31/336 ,  A61K31/365 ,  A61K31/40 ,  A61K31/4045 ,  A61K31/436 ,  A61K31/4412 ,  A61K31/4418

摘要： The present disclosure, in at least certain embodiments, is directed to shikimate (shikimic acid) analogues and compositions thereof, kits which contain the shikimate analogues or compositions thereof, and methods of use of the compounds and compositions for treating epithelial surfaces before or following exposure to irritants, allergens, and toxic agents (for example, urushiol).

公开(公告)号：EP3344276A1

公开(公告)日：2018-07-11

申请号：EP16843042.9

申请日：2016-09-02

申请人： The Board of Regents of the University of Oklahoma

发明人： BALLARD, Jimmy, D. ,  LARABEE, Jason, L.

IPC分类号： A61K38/16 ,  A61K39/40 ,  C07K14/33

摘要： Disclosed are synthetic peptides and peptide compositions, including peptide conjugates, that can ameliorate and/or block the cytotoxicity of C. difficile TcdB toxin, and methods of their use for inhibiting the activity of TcdB and protecting against damage during C. difficile disease, and/or for use as cell penetrating peptides for enhancing the delivery of particular heterogenous molecules into cells.