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公开(公告)号：EP3919704A1
公开(公告)日：2021-12-08
申请号：EP20382488.3
申请日：2020-06-05
发明人： SOSA DÍAZ-SAAVEDRA, José Antonio , GARCÍA SÁNCHEZ, Héctor Julián , LLORCA AFONSO, Eva María , ALONSO ROHNER, Evelyn
摘要： The present invention relates to an insulation board for being assembled on the roof of a construction, wherein said insulation board gives form to a self-ventilated air chamber in conjunction with said roof. The invention also relates to a method of assembly of at least one pair of said insulation boards, a structure assembled from two or more of said insulation boards being obtained.
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公开(公告)号：EP3779849A1
公开(公告)日：2021-02-17
申请号：EP19776863.3
申请日：2019-03-27
发明人： CABRUJA CASAS, Enric , LOZANO FANTOBA, Manuel , PÉREZ SÁNCHEZ, Jaume , CALDUCH GINER, Josep , SOSA GONZÁLEZ, Carlos Javier , FERRER BALLESTER, Miguel Ángel , MONTIEL NELSON, Juan Antonio , AFONSO LÓPEZ, Juan Manuel
摘要： The invention relates to a device placed on the operculum to monitor the metabolic state and well-being of fish through joint, simultaneous measurements of breathing frequency and physical activity via a plurality of accelerations that are coplanar (x and y axes) and normal to the operculum (z axis). The substrate is flexible and is covered with an water-resistant coating, which contains an electronic circuit with an acceleration sensor (208), a control unit (202), a microcontroller (206) configured to execute at least one activity-monitoring routine, a memory (210) and a battery (204). Data are collected via an external unit (201) which can optionally process them in a complete or partial manner. This type of measurement can be processed jointly with another type of measurement, obtained from other sensors of environmental parameters.
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公开(公告)号：EP3461788A1
公开(公告)日：2019-04-03
申请号：EP18173213.2
申请日：2017-03-02
发明人： MONZÓN MAYOR, Maximina , ROMERO ALEMÁN, María del Mar , HERNÁNDEZ RODRÍGUEZ, José Enrique , PÉREZ GALVÁN, José Manuel
IPC分类号： B82Y5/00 , A61L27/54 , A61L27/18 , A61L27/36 , A61L27/48 , A61L31/00 , A61L31/06 , A61L15/26 , A61L15/40 , A61L17/10 , A61L31/16 , A61L17/00
摘要： The present invention provides hybrid nanofibers that comprise a mixture of components of a honey and a synthetic polymer. The invention further provides a method for producing the hybrid nanofibers. The hybrid nanofibers of the invention can be used in tubular prostheses for nerve reconnection following peripheral nerve axotomy, in surgical meshes, dressings and sutures, to improve the reinnervation, and therefore the functional recovery from injuries in diverse organs such as the skin (e.g. burns, ulcers, surgical incisions, fistulas, etc.).
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公开(公告)号：EP4242226A1
公开(公告)日：2023-09-13
申请号：EP22382223.0
申请日：2022-03-09
发明人： FERNÁNDEZ HERRERO, Luis Ángel , CASASNOVAS SUELVES, José María , MARGOLLES AZPIAZU, Yago , NORIEGA FEBRERO, María de los Ángeles , GASTAMINZA LANDART, Pablo , GARAIGORTA DE DIOS, Urtzi , MARTÍN ACEBES, Miguel Ángel , SAIZ CALAHORRA, Juan Carlos , CORBERA SÁNCHEZ, Juan Alberto
摘要： The invention relates to a nanobody directed against the receptor binding domain (RBD) of spike protein from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), to a fusion protein comprising said nanobody, and to a heavy chain antibody comprising two heavy chains, wherein each heavy chain comprises said fusion protein. The invention also relates to a bivalent construction comprising two nanobodies, wherein said two nanobodies are linked by a peptide bond. The invention also relates to a nucleic acid encoding the said nanobody, fusion protein or bivalent construction, to a vector comprising said nucleic acid, to a host cell comprising said nucleic acid or said vector, and to a pharmaceutical composition comprising said nanobody, fusion protein, heavy chain antibody or bivalent construction. The invention also relates to the medical uses of said nanobody, fusion protein, heavy chain antibody, bivalent construction or pharmaceutical composition for use in the treatment and/or prevention of an infection caused by SARS-CoV-2, and to a method for diagnosing an infection SARS-CoV-2 in a subject comprising contacting a sample from the subject with said nanobody, fusion protein, heavy chain antibody or bivalent construction.
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公开(公告)号：EP4242225A1
公开(公告)日：2023-09-13
申请号：EP22382222.2
申请日：2022-03-09
发明人： FERNÁNDEZ HERRERO, Luis Ángel , CASASNOVAS SUELVES, José María , MARGOLLES AZPIAZU, Yago , NORIEGA FEBRERO, María de los Ángeles , GASTAMINZA LANDART, Pablo , GARAIGORTA DE DIOS, Urtzi , MARTÍN ACEBES, Miguel Ángel , SAIZ CALAHORRA, Juan Carlos , CORBERA SÁNCHEZ, Juan Alberto
摘要： The invention relates to a nanobody directed against the receptor binding domain (RBD) of spike protein from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), to a fusion protein comprising said nanobody, and to a heavy chain antibody comprising two heavy chains, wherein each heavy chain comprises said fusion protein. The invention also relates to a bivalent construction comprising two nanobodies, wherein said two nanobodies are linked by a peptide bond. The invention also relates to a nucleic acid encoding the said nanobody, fusion protein or bivalent construction, to a vector comprising said nucleic acid, to a host cell comprising said nucleic acid or said vector, and to a pharmaceutical composition comprising said nanobody, fusion protein, heavy chain antibody or bivalent construction. The invention also relates to the medical uses of said nanobody, fusion protein, heavy chain antibody, bivalent construction or pharmaceutical composition for use in the treatment and/or prevention of an infection caused by SARS-CoV-2, and to a method for diagnosing an infection SARS-CoV-2 in a subject comprising contacting a sample from the subject with said nanobody, fusion protein, heavy chain antibody or bivalent construction.
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6.发明公开
公开(公告)号：EP3545491A1
公开(公告)日：2019-10-02
申请号：EP16798771.8
申请日：2016-11-22
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公开(公告)号：EP4349429A1
公开(公告)日：2024-04-10
申请号：EP22810698.5
申请日：2022-04-28
IPC分类号： A63B31/10
摘要： Disclosed is an ergonomic swimming paddle, comprising a main plate (1) and an auxiliary bendable plate (2), removably connected to the main plate (1). In this way, although greater force is needed to execute each stroke, at a fixed swimming speed, the overall stroke power increases. The ergonomic swimming paddle has additional advantages, such as boosting hand position perception and preventing abrupt changes of direction of the upper limbs, thereby improving swimming efficiency in terms of hydrodynamic forces. The paddle is suitable to be used by swimmers of all levels and ages to improve their sporting performance.
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公开(公告)号：EP4242228A1
公开(公告)日：2023-09-13
申请号：EP22382228.9
申请日：2022-03-09
发明人： FERNÁNDEZ HERRERO, Luis Ángel , CASASNOVAS SUELVES, José María , MARGOLLES AZPIAZU, Yago , NORIEGA FEBRERO, María de los Ángeles , GASTAMINZA LANDART, Pablo , GARAIGORTA DE DIOS, Urtzi , MARTÍN ACEBES, Miguel Ángel , SAIZ CALAHORRA, Juan Carlos , CORBERA SÁNCHEZ, Juan Alberto
摘要： The invention relates to a nanobody directed against the receptor binding domain (RBD) of spike protein from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), to a fusion protein comprising said nanobody, and to a heavy chain antibody comprising two heavy chains, wherein each heavy chain comprises said fusion protein. The invention also relates to a bivalent construction comprising two nanobodies, wherein said two nanobodies are linked by a peptide bond. The invention also relates to a nucleic acid encoding the said nanobody, fusion protein or bivalent construction, to a vector comprising said nucleic acid, to a host cell comprising said nucleic acid or said vector, and to a pharmaceutical composition comprising said nanobody, fusion protein, heavy chain antibody or bivalent construction. The invention also relates to the medical uses of said nanobody, fusion protein, heavy chain antibody, bivalent construction or pharmaceutical composition for use in the treatment and/or prevention of an infection caused by SARS-CoV-2, and to a method for diagnosing an infection SARS-CoV-2 in a subject comprising contacting a sample from the subject with said nanobody, fusion protein, heavy chain antibody or bivalent construction.
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9.发明公开
公开(公告)号：EP4046779A1
公开(公告)日：2022-08-24
申请号：EP22382036.6
申请日：2022-01-20
IPC分类号： B29C64/329 , B29C64/336 , B01J8/00 , B01J19/24 , B22F10/00 , B29B7/60
摘要： Homogeneous material mixing device adapted for an extrusion printer comprising a cyclone (10), a pipe (21) which transports to the cyclone (10) gas or the mixture of gas with particles of the first material, at least a second pipe (22) which transports gas or a mixture of the gas with particles of a second material to the cyclone (10), and regulation means (4) configured to continuously regulate the gas flow rate circulating through both pipes (21,22) ensuring a constant total inflow rate in the cyclone (10) through each pipe (21,22) with a predefined amount of particles of the corresponding material, the mixing of both materials and the separation of the gas from the mixture, or the separation of the gas from the first material or second material being carried out in the cyclone (10). Operating method for the device.
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公开(公告)号：EP2872194A1
公开(公告)日：2015-05-20
申请号：EP13735021.1
申请日：2013-07-10
IPC分类号： A61M3/02
CPC分类号： A61M25/0017 , A61M39/223 , A61M2025/0018 , A61M2039/224 , A61M2205/7536
摘要： The invention relates to a bladder catheter (10), comprising a tube (12), wherein the tube (12) has an insertion section (14) for inserting into a urinary bladder through a urethra and wherein the tube (12) has a connection section (18) for connecting connection elements, wherein fluid can be drained from the urethra at the connection section (18) via the insertion section (14), wherein a closable valve (22) is arranged between the insertion section (14) and the connection section (18) in such a way that the discharge of fluid from the connection section (18) can be prevented while the valve (22) is closed.
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