公开(公告)号：EP3473761A1

公开(公告)日：2019-04-24

申请号：EP18201779.8

申请日：2012-11-01

申请人： Twins Corporation ,  Osada, Masakazu ,  Yang, Liming ,  Hsieh, Tsung Jen

发明人： Osada, Masakazu ,  Yang, Liming ,  Hsieh, Tsung Jen ,  Kajiwara, Ryuji

IPC分类号： D04C1/12 ,  A43C1/02 ,  A43C1/00

摘要： In the conventional lace with knobby portions having elastic rubber core, there is difference in degree of stretch between both ends and core of the knobby portion. Therefore, there are a portion that is subjected to heavy stretching force and a portion that is subjected to no stretching force, and when large strain is accumulated at the boundary between the portions subjected to different stretching forces and the strain reaches the limit, the lace ruptures. In order to solve the above problem, we provide a lace provided with tubular lace body of elastic material, comprising knobby portions repeatedly placed at intervals, of which diameter vary depending on tension on the knobby portion in an axial direction.

公开(公告)号：EP1223963A2

公开(公告)日：2002-07-24

申请号：EP00965696.8

申请日：2000-10-06

申请人： Zhang, Li ,  Zhang, Zhu Xu ,  Yang, Liming

发明人： Zhang, Li ,  Zhang, Zhu Xu ,  Yang, Liming

IPC分类号： A61K38/17 ,  C12N5/06 ,  C12N5/08 ,  A61K39/395 ,  A61K38/13 ,  A61K38/20 ,  C07K16/18 ,  A61P37/04 ,  A61P37/06

CPC分类号： A61K38/13 ,  A61K35/17 ,  A61K38/1709 ,  A61K38/19 ,  A61K38/2066 ,  A61K39/001 ,  A61K48/00 ,  A61K2039/505 ,  A61K2039/515 ,  C07K16/28 ,  C12N5/0636 ,  C12N2501/599 ,  C12N2501/60 ,  A61K2300/00

摘要： Novel cells and molecules involved in immune regulation are disclosed. The novel cells are regulatory T cells having the phenotype CD + alpha beta TCR CD4 CD8 CD44 CD28 NK1 1-. The regulatory cells express high levels of Ly-6A and osteopontin while non-regulatory cells do not. Inhibiting Ly-6A or osteopontin inhibits the suppressive properties of the cells.

公开(公告)号：EP2749678B1

公开(公告)日：2018-10-24

申请号：EP12880383.0

申请日：2012-11-01

申请人： Twins Corporation ,  Osada, Masakazu ,  Yang, Liming ,  Hsieh, Tsung Jen

发明人： OSADA, Masakazu ,  YANG, Liming ,  HSIEH, Tsung Jen ,  KAJIWARA, Ryuji

IPC分类号： D04C1/12 ,  A43C1/02 ,  A43C1/00

CPC分类号： A43C9/00 ,  A43C1/003 ,  A43C1/02 ,  D04C1/02 ,  Y10T24/3787

摘要： In the conventional lace with knobby portions having elastic rubber core, there is difference in degree of stretch between both ends and core of the knobby portion. Therefore, there are a portion that is subjected to heavy stretching force and a portion that is subjected to no stretching force, and when large strain is accumulated at the boundary between the portions subjected to different stretching forces and the strain reaches the limit, the lace ruptures. In order to solve the above problem, we provide a lace provided with tubular lace body of elastic material, comprising knobby portions repeatedly placed at intervals, of which diameter vary depending on tension on the knobby portion in an axial direction.

公开(公告)号：EP2749678A4

公开(公告)日：2015-04-22

申请号：EP12880383

申请日：2012-11-01

申请人： TWINS CORP ,  OSADA MASAKAZU ,  YANG LIMING ,  HSIEH TSUNG JEN

发明人： OSADA MASAKAZU ,  YANG LIMING ,  HSIEH TSUNG JEN ,  KAJIWARA RYUJI

IPC分类号： D04C1/12 ,  A43C1/00 ,  A43C1/02

CPC分类号： A43C9/00 ,  A43C1/003 ,  A43C1/02 ,  D04C1/02 ,  Y10T24/3787

摘要： In the conventional lace with knobby portions having elastic rubber core, there is difference in degree of stretch between both ends and core of the knobby portion. Therefore, there are a portion that is subjected to heavy stretching force and a portion that is subjected to no stretching force, and when large strain is accumulated at the boundary between the portions subjected to different stretching forces and the strain reaches the limit, the lace ruptures. In order to solve the above problem, we provide a lace provided with tubular lace body of elastic material, comprising knobby portions repeatedly placed at intervals, of which diameter vary depending on tension on the knobby portion in an axial direction.

公开(公告)号：EP2749678A1

公开(公告)日：2014-07-02

申请号：EP12880383.0

申请日：2012-11-01

申请人： Twins Corporation ,  Osada, Masakazu ,  Yang, Liming ,  Hsieh, Tsung Jen

发明人： OSADA, Masakazu ,  YANG, Liming ,  HSIEH, Tsung Jen ,  KAJIWARA, Ryuji

IPC分类号： D04C1/12 ,  A43C1/02

CPC分类号： A43C9/00 ,  A43C1/003 ,  A43C1/02 ,  D04C1/02 ,  Y10T24/3787

摘要： In the conventional lace with knobby portions having elastic rubber core, there is difference in degree of stretch between both ends and core of the knobby portion. Therefore, there are a portion that is subjected to heavy stretching force and a portion that is subjected to no stretching force, and when large strain is accumulated at the boundary between the portions subjected to different stretching forces and the strain reaches the limit, the lace ruptures. In order to solve the above problem, we provide a lace provided with tubular lace body of elastic material, comprising knobby portions repeatedly placed at intervals, of which diameter vary depending on tension on the knobby portion in an axial direction.

摘要翻译： 在具有弹性橡胶芯的旋钮部分的常规蕾丝中，在纽扣部分的两端和芯之间的拉伸程度是不同的。 因此，存在承受较大拉伸力的部分和不具有拉伸力的部分，并且当受到不同拉伸力的部分之间的边界处的大应变积聚并且应变达到极限时，花边 破裂。 为了解决上述问题，本发明提供了一种带弹性材料的管状蕾丝体的花边，其包括间隔重复设置的旋钮部分，其直径根据旋钮部分沿轴向的张力而变化。