公开(公告)号：EP1776474A2

公开(公告)日：2007-04-25

申请号：EP05776987.9

申请日：2005-07-21

申请人： (OSI) EYETECH, INC.

发明人： SHIMA, David, T. ,  CALIA, Pericles ,  ROBINSON, Gregory, S. ,  WING, John, P. ,  MULLIN, Lori, M. ,  SMITH, Lillian, M. ,  SINANI, Ervin

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6837 ,  C12Q1/6816 ,  C12Q2561/125 ,  C12Q2561/101 ,  C12Q2525/205 ,  C12Q2533/107 ,  C12Q2537/125 ,  C12Q2531/113 ,  C12Q2525/155

摘要： The invention provides methods and compositions for detecting and/or quantifying modified nucleic acid oligonucleotides. These methods and compositions are useful for detecting and quantifying diagnostic and/or therapeutic synthetic modified oligonucleotides, such as aptamers, RNAi, siRNA, antisense oligonucleotides or ribozymes in a biological sample.