公开(公告)号：EP0293858B1

公开(公告)日：1994-03-23

申请号：EP88108779.5

申请日：1988-06-01

申请人： ABBOTT LABORATORIES

发明人： Pumphrey, John G. ,  Garrett, Paul E. ,  Durley, Benton A., III ,  Pumphrey, Edward G. ,  Davis, Charles L. ,  Spritzer, Lawrence ,  Clark, Frederic L.

IPC分类号： G01N27/28 ,  G01N33/487

CPC分类号： G01N33/492

公开(公告)号：EP0293858A3

公开(公告)日：1990-07-04

申请号：EP88108779.5

申请日：1988-06-01

申请人： ABBOTT LABORATORIES

发明人： Pumphrey, John G. ,  Garrett, Paul E. ,  Durley, Benton A., III ,  Pumphrey, Edward G. ,  Davis, Charles L. ,  Spritzer, Lawrence ,  Clark, Frederic L.

IPC分类号： G01N27/28 ,  G01N33/487

CPC分类号： G01N33/492

摘要： Apparatus for measuring electrolyte concen­trations in fluid samples is provided. The apparatus includes an ion selective electrode having a plurality of ion selective detection sites. Each site has an affinity for a preselected electrolyte of interest and generates a potential having a magnitude related to the concentration of the corresponding electrolyte in the sample. A voltage to optical transducer circuit is provided to convert the voltage differentials to optical signals having intensity related to the concentration of the electrolytes in a first embodiment, a digital code related to the concentration of the electrolytes in a second embodiment, and an optical absorption or density value related to the concentration of the electrolytes in a third embodiment. The optical signals are suitable for detection by conventional optical detector apparatus of assay instruments and may be processed using conven­tional two point linear interpolation techniques to determine the concentrations of the preselected electrolytes.

公开(公告)号：EP0178567A3

公开(公告)日：1987-11-11

申请号：EP85112703

申请日：1985-10-08

申请人： ABBOTT LABORATORIES

发明人： Davis, Charles L.

IPC分类号： G05D23/26 ,  H01H37/58

CPC分类号： H01H37/585 ,  G05D23/1902 ,  G05D23/26

摘要： An apparatus and method for controlling the operating temperatures and differential temperature of a curie effect temperature sensing switch is disclosed. The temperature switch is adapted to provide temperature control of a cold plate in a reagent refrigerator. The temperature switch activates cold plate cooling devices when the cold plate temperature is above a first operating temperature and deactivates the cold plate cooling devices when the cold plate temperature is below a second operating temperature. An electromagnet is fixed external of and relative to the temperature switch so that the strength of the external magnetic field sets the operating temperatures of the temperature switch. A potentiometer is used to incrementally vary the current supplied to the electromagnet to thereby incrementally adjust the strength of the external magnetic field and the operating temperatures. A microprocessor may be provided to adjust the voltage supply of the potentiometer, which allows remote control of the operating temperatures. A second potentiometer is connected to the electromagnet so that it incrementally adjusts the current passed to the electromagnet as a function of whether the temperature switch is open or closed. Incremental adjustment of the second potentiometer provides incremental adjustment of the temperature differential. A monitor provides a warning signal if the temperature switch does not open and close within a predetermined time interval.

公开(公告)号：EP0178567B1

公开(公告)日：1992-04-01

申请号：EP85112703.5

申请日：1985-10-08

申请人： ABBOTT LABORATORIES

发明人： Davis, Charles L.

IPC分类号： G05D23/26 ,  H01H37/58

CPC分类号： H01H37/585 ,  G05D23/1902 ,  G05D23/26

公开(公告)号：EP0293858A2

公开(公告)日：1988-12-07

申请号：EP88108779.5

申请日：1988-06-01

申请人： ABBOTT LABORATORIES

发明人： Pumphrey, John G. ,  Garrett, Paul E. ,  Durley, Benton A., III ,  Pumphrey, Edward G. ,  Davis, Charles L. ,  Spritzer, Lawrence ,  Clark, Frederic L.

IPC分类号： G01N27/28 ,  G01N33/487

CPC分类号： G01N33/492

摘要： Apparatus for measuring electrolyte concen­trations in fluid samples is provided. The apparatus includes an ion selective electrode having a plurality of ion selective detection sites. Each site has an affinity for a preselected electrolyte of interest and generates a potential having a magnitude related to the concentration of the corresponding electrolyte in the sample. A voltage to optical transducer circuit is provided to convert the voltage differentials to optical signals having intensity related to the concentration of the electrolytes in a first embodiment, a digital code related to the concentration of the electrolytes in a second embodiment, and an optical absorption or density value related to the concentration of the electrolytes in a third embodiment. The optical signals are suitable for detection by conventional optical detector apparatus of assay instruments and may be processed using conven­tional two point linear interpolation techniques to determine the concentrations of the preselected electrolytes.

摘要翻译： 提供了用于测量流体样品中电解质浓度的装置。 该装置包括具有多个离子选择性检测部位的离子选择电极。 每个位点对预先选定的感兴趣的电解质具有亲和性，并产生具有与样品中相应电解质浓度相关的量级的电位。 提供了一种对光学换能器电路的电压，以将第一实施例中的电压差与具有与电解质的浓度相关的强度的光信号转换成与第二实施例中的电解质的浓度有关的数字码，以及光学吸收或 与第三实施方案中的电解质的浓度有关的浓度值。 光学信号适合于通过常规的检测仪器的光学检测器检测，并且可以使用传统的两点线性内插技术来处理以确定预选的电解质的浓度。

公开(公告)号：EP0178567A2

公开(公告)日：1986-04-23

申请号：EP85112703.5

申请日：1985-10-08

申请人： ABBOTT LABORATORIES

发明人： Davis, Charles L.

IPC分类号： G05D23/26 ,  H01H37/58

CPC分类号： H01H37/585 ,  G05D23/1902 ,  G05D23/26

摘要： An apparatus and method for controlling the operating temperatures and differential temperature of a curie effect temperature sensing switch is disclosed. The temperature switch is adapted to provide temperature control of a cold plate in a reagent refrigerator. The temperature switch activates cold plate cooling devices when the cold plate temperature is above a first operating temperature and deactivates the cold plate cooling devices when the cold plate temperature is below a second operating temperature. An electromagnet is fixed external of and relative to the temperature switch so that the strength of the external magnetic field sets the operating temperatures of the temperature switch. A potentiometer is used to incrementally vary the current supplied to the electromagnet to thereby incrementally adjust the strength of the external magnetic field and the operating temperatures. A microprocessor may be provided to adjust the voltage supply of the potentiometer, which allows remote control of the operating temperatures. A second potentiometer is connected to the electromagnet so that it incrementally adjusts the current passed to the electromagnet as a function of whether the temperature switch is open or closed. Incremental adjustment of the second potentiometer provides incremental adjustment of the temperature differential. A monitor provides a warning signal if the temperature switch does not open and close within a predetermined time interval.