公开(公告)号：EP1124527A2

公开(公告)日：2001-08-22

申请号：EP99933494.9

申请日：1999-06-04

申请人： ABBOTT LABORATORIES

发明人： FELICELLI, Robert ,  GRABENKORT, Richard ,  LASAITIS, Con, A. ,  SMITH, Gary, N. ,  ZIEGLER, John, S.

IPC分类号： A61J1/00

CPC分类号： A61J1/2096 ,  A61J1/2075 ,  A61J1/2082

摘要： A container for holding a concentrated drug for a mixing system includes a barrel with a cover structure including a delivery passage at a first end and a closing structure at an opposite, second end. A female Luer lock fitting defines the delivery passage at the first end. The closing structure and the female Luer lock fitting can each be formed integrally with the barrel, or the closing structure can be a slidable stopper. The closing structure may also include a holder. The holder is constructed to move between two positions. In the first position, the holder is in an elevated position on the second end of the barrel. The barrel can vent vapor around the cover piece. In the second position, the holder is depressed onto the barrel and it cannot vent vapor. The cover structure may include a snap-on cover piece to fit over the first end. The cover piece includes the female Luer lock fitting. The cover piece functions similar to the holder. The container can be used in a mixing system which includes a diluent syringe with a barrel having a discharge passage at a first end, and a piston slidably and sealingly disposed in the diluent syringe barrel to define a diluent chamber adjacent the discharge passage. The syringe includes a male Luer lock fitting at its first end for releasably connecting to the female Luer lock fitting of the container. Diluent can be passed from the syringe into the container to mix with the concentrated drug and the resultant mixture can then be drawn from the container for administering to a patient.

公开(公告)号：EP1075293A1

公开(公告)日：2001-02-14

申请号：EP99921553.6

申请日：1999-04-30

申请人： ABBOTT LABORATORIES

发明人： ZIEGLER, John, S.

IPC分类号： A61M5/315

CPC分类号： A61M5/31511 ,  A61M5/31515 ,  A61M5/502 ,  A61M2005/3121 ,  A61M2005/31506 ,  A61M2005/31508

摘要： The syringe assembly (10) includes a syringe barrel (12) having an interior surface (22) and a substantially closed discharge end (24) defining a discharge opening (26). A stop (34) is mounted on the interior surface (22) of the syringe barrel (12). A piston (14) is slidably disposed within the syringe barrel (12). The piston has a forward-most sealing surface and the rearward-most sealing surface. The forward-most sealing surface (39) and the rearward-most sealing surface (45) are spaced a first distance from one another. The piston (14) is movable between a first position and a second position. The plunger rod (18) has at least one finger (76) extending therefrom, the at least one finger (76) having a distal end portion constructed to engage the stop (34) when the piston (14) is in its second position. The distal end portion of the at least one finger (76) is positioned no more than the first distance from the stop (34) when the piston (14) is in its first position.

摘要翻译： 注射器组件（10）包括具有内表面（22）和限定排出口（26）的基本封闭的排出端（24）的注射器筒（12）。 止动件（34）安装在注射器筒（12）的内表面（22）上。 活塞（14）可滑动地设置在注射器筒（12）内。 活塞具有最前面的密封表面和最后面的密封表面。 最前面的密封表面（39）和最后面的密封表面（45）彼此隔开第一距离。 活塞（14）可在第一位置和第二位置之间移动。 柱塞杆（18）具有从其延伸的至少一个指状件（76），该至少一个指状件（76）具有构造成当活塞（14）处于其第二位置时接合止动件（34）的远端部分。 当活塞（14）处于其第一位置时，至少一个指状件（76）的远端部分定位成不超过距止动件（34）的第一距离。

公开(公告)号：EP1257310A2

公开(公告)日：2002-11-20

申请号：EP01912842.0

申请日：2001-02-20

申请人： Abbott Laboratories

发明人： GRABENKORT, Richard, W. ,  ZIEGLER, John, S. ,  SPRAGUE, Karl, J.

IPC分类号： A61M5/315

CPC分类号： A61M5/31596 ,  A61M5/31595 ,  A61M2005/31508 ,  A61M2005/31598

摘要： A syringe may include various forms of a releasable stop adapted to selectively limit the travel of the syringe plunger within the syringe barrel such that a first amount of therapeutic substance may be discharged from the syringe while a residual supply of the therapeutic substance remains in the syringe. Movement of the plunger is permitted to displace the residual supply of fluid from the barrel. Syringes according to the invention find particular application as diluent syringes in a wet/dry drug delivery syringe system having two cooperating syringe barrels in which the residual supply of diluent in the diluent syringe may be used to flush additional and otherwise wasted drug from a drug syringe barrel.

公开(公告)号：EP0564581A1

公开(公告)日：1993-10-13

申请号：EP92903544.0

申请日：1991-12-23

申请人： ABBOTT LABORATORIES

发明人： KOLBER, Chris, M. ,  BRYANT, Peter, L. ,  LARKIN, Mark, E. ,  KARAS, Peter, J. ,  ZIEGLER, John, S.

IPC分类号： A61J1 ,  A61M5

CPC分类号： A61J1/2096 ,  A61J1/201 ,  A61J1/2013 ,  A61M5/2429 ,  Y10S604/905

摘要： Système de stockage et d'acheminement (10) de médicament comprenant un flacon (18) contenant un médicament, une seringue (14) ainsi qu'un adaptateur (16) permettant de fixer le flacon à l'adaptateur (16). Ledit flacon (12) comporte un obturateur (28) pouvant être percé ainsi qu'une jupe (34) entourant l'extérieur du flacon (18). La seringue (14) est traversée par une canule (44) s'étendant longitudinalement. L'adaptateur (16) fixe le flacon (12) à la seringue (14) d'une manière permettant une communication entre l'intérieur du flacon (18) et la canule (44) s'étendant dans la seringue. Le système (10) permet également la fixation de la seringue (14) à un récipient (90) rempli d'un diluant et à un moyen d'acheminement du diluant dans ledit flacon (12) renvoyant ensuite dans le récipient (90) la solution mélangée.