公开(公告)号：EP2655415A4

公开(公告)日：2016-03-09

申请号：EP11850224

申请日：2011-12-21

申请人： ABBVIE INC

发明人： WU CHENGBIN ,  YING HUA ,  GHAYUR TARIQ ,  GOODREAU CARRIE ,  BARDWELL PHILIP

IPC分类号： C07K16/46 ,  C07K16/24 ,  C07K16/26 ,  C07K16/28 ,  C07K16/32

CPC分类号： C07K16/468 ,  A61K2039/505 ,  C07K16/241 ,  C07K16/244 ,  C07K16/26 ,  C07K16/2809 ,  C07K16/2863 ,  C07K16/2887 ,  C07K16/32 ,  C07K2317/31 ,  C07K2317/35 ,  C07K2317/56 ,  C07K2317/64 ,  C07K2317/73 ,  C07K2317/76 ,  C07K2317/92 ,  G01N2333/525 ,  G01N2333/54 ,  G01N2405/00

摘要： The present invention provides engineered multivalent and multispecific binding proteins, as well as methods of making them. Methods for using the multivalent and multispecific binding proteins of the invention in the prevention, diagnosis, and/or treatment of disease are also provided.