公开(公告)号：EP3227447A4

公开(公告)日：2018-07-11

申请号：EP15866342

申请日：2015-12-03

申请人： AGILENT TECHNOLOGIES INC

发明人： RYAN DANIEL E ,  DELLINGER DOUGLAS J ,  SAMPSON JEFFREY R ,  KAISER ROBERT ,  MYERSON JOEL

IPC分类号： C12N15/113 ,  C07H21/00 ,  C12N9/22

CPC分类号： C12N15/111 ,  C07H21/02 ,  C12N9/22 ,  C12N15/113 ,  C12N15/907 ,  C12N2310/10 ,  C12N2310/20 ,  C12N2310/312 ,  C12N2310/315 ,  C12N2310/321 ,  C12N2310/322 ,  C12N2310/323 ,  C12N2310/3231 ,  C12N2310/333 ,  C12N2310/335 ,  C12N2310/346 ,  C12N2310/3517 ,  C12N2310/531 ,  C12N2320/51 ,  C12N2320/53 ,  C12N2330/31 ,  C12Q1/6876 ,  C12N2310/3521 ,  C12N2310/3533

摘要： The present invention relates to modified guide RNAs and their use in clustered, regularly interspaced, short palindromic repeats (CRISPR)/CRISPR-associated (Cas) systems.