专利检索 ap:("APOTEX INC.") AND inv:"TAM, Tim Fat" 第 1 页

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发明公开
ISOPROPANOLATE OF AZITHROMYCIN AND METHOD OF MANUFACTURING 审中-公开
标题翻译：阿齐霉素和制造方法的Isopropanolates

公开(公告)号：EP1615941A1

公开(公告)日：2006-01-18

申请号：EP04721787.2

申请日：2004-03-19

申请人： APOTEX INC.

发明人： TAM, Tim Fat , KARIMIAN, Khashayar , HU, Shui, Sheng , CHOW, Anna , STOREY, Richard William

IPC分类号： C07H17/00 , C07H17/08 , A61K31/7048 , A61P31/04

CPC分类号： C07H17/08 , C07H17/00

摘要： Azithromycin isopropanolate of the empirical formula azithromycin: [H20]x: [isopropanol]y is obtained from the crystallization of azithromycin in isopropanol and water. The x and y values is confirmed by single X-ray diffraction determination. In one embodiment x=1.5 and y=0.25. In another embodiment x=0.75 and y=0.5.