公开(公告)号：EP1879886A4

公开(公告)日：2010-09-08

申请号：EP06758821

申请日：2006-05-01

申请人： ARRAY BIOPHARMA INC

发明人： HANS JEREMY ,  WALLACE ELI M ,  ZHAO QIAN ,  ALLEN SHELLEY ,  LAIRD ELLEN ,  LYSSIKATOS JOSEPH P ,  ROBINSON JOHN E ,  CORRETTE CHRISTOPHER P ,  DELISLE ROBERT KIRK ,  VOEGTLI WALTER CHARLES

IPC分类号： C07D417/04 ,  C07D417/14 ,  C07D419/04 ,  C07D471/04 ,  C07D487/04 ,  C07D495/04 ,  C07D513/04

CPC分类号： C07D513/04 ,  C07D285/12 ,  C07D417/04 ,  C07D417/14 ,  C07D419/04 ,  C07D471/04 ,  C07D487/04 ,  C07D495/04 ,  C07D497/04 ,  C07F9/65395

摘要： This invention relates to inhibitors of mitotic kinesins, particularly KSP, and methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing the inhibitors and pharmaceutical compositions in the treatment and prevention of various disorders.