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公开(公告)号:EP1532177B1
公开(公告)日:2008-10-22
申请号:EP03733654.2
申请日:2003-06-04
发明人: Fraser, John David
IPC分类号: C07K19/00 , C07K14/00 , C07K14/315 , C07K16/12 , A61K35/74 , A61K39/00 , A61K39/09 , A61K39/39 , C12N1/20 , C12N15/31 , C07H19/00 , C12Q1/68
CPC分类号: C07K14/315 , A61K39/092 , A61K39/385 , A61K2039/6037
摘要: The invention relates to immunomodulators. In particular the invention relates to specific immunomodulators based on the superantigen SMEZ-2 and more particularly based on mutants of the superantigen SMEZ-2, which are adapted to target antigen-presenting-cells for the purpose of enhancing or suppressing a host immune response.
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公开(公告)号:EP1532177A2
公开(公告)日:2005-05-25
申请号:EP03733654.2
申请日:2003-06-04
发明人: Fraser, John David
IPC分类号: C07K19/00 , C07K14/00 , C07K14/315 , C07K16/12 , A61K35/74 , A61K39/00 , A61K39/09 , A61K39/39 , C12N1/20 , C12N15/31 , C07H19/00 , C12Q1/68
CPC分类号: C07K14/315 , A61K39/092 , A61K39/385 , A61K2039/6037
摘要: The invention relates to immunomodulators. In particular the invention relates to specific immunomodulators based on the superantigen SMEZ-2 and more particularly based on mutants of the superantigen SMEZ-2, which are adapted to target antigen-presenting-cells for the purpose of enhancing or suppressing a host immune response.
摘要翻译: 本发明涉及免疫调节剂。 特别地,本发明涉及基于超抗原SMEZ-2并且更具体地基于超抗原SMEZ-2的突变体的特定免疫调节剂,其适于靶向抗原呈递细胞以增强或抑制宿主免疫应答。
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