专利检索 ap:("AbbVie Inc.") AND inv:"COWART, Marlon D." 第 1 页

1.

发明公开
6-HETEROARYLOXY- AND 6-ARYLOXY-QUINOLINE-2-CARBOXAMIDES AND USES THEREOF 审中-公开
标题翻译： 6-杂芳氧基和6-芳氧基喹啉-2-羧酰胺和其用途

公开(公告)号：EP3102569A1

公开(公告)日：2016-12-14

申请号：EP15705447.9

申请日：2015-02-04

申请人： AbbVie Inc.

发明人： BOGDAN, Andrew , COWART, Marlon D. , DEGOEY, DavidA. , JINKERSON, Tammie, K. , KOENIG, John R. , KORT, Michael E. , LIU, Bo , MATULENKO, Mark A. , NELSON, Derek W. , PATEL, Meena V. , PELTIER, Hillary , SCANIO, Marc J. , WAKEFIELD, Brian D.

IPC分类号： C07D401/14 , C07D215/48 , C07D401/12 , C07D405/12 , C07D409/12 , C07D417/12 , C07D487/04 , C07D487/08 , A61K31/498 , A61K31/4709 , A61K31/5377 , A61P25/00 , A61P29/00

CPC分类号： C07D215/48 , C07D401/12 , C07D401/14 , C07D405/12 , C07D405/14 , C07D409/12 , C07D409/14 , C07D417/12 , C07D417/14 , C07D471/04 , C07D487/04 , C07D487/08

摘要： Compounds of formula (I) and pharmaceutically acceptable salts, esters, amides, or radiolabelled forms thereof, wherein R1, R2, and R3 are as defined in the specification, are useful in treating conditions or disorders prevented by or ameliorated by voltage-gated sodium channels, e.g., Nav1.7 and/or Nav1.8. Methods for making the compounds are disclosed. Also disclosed are pharmaceutical compositions of compounds of formula (I), and methods for using such compounds and compositions.