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1.DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF 审中-公开
标题翻译: 双重可变域 - IMMUNGLOBULINE IHRE VERWENDUNGEN公开(公告)号:EP3002299A1
公开(公告)日:2016-04-06
申请号:EP15189272.6
申请日:2009-06-03
申请人: AbbVie Inc.
发明人: GHAYUR, Tariq , ISAKSON, Peter, C. , OLSON, Lisa, M. , WU, Chengbin , HUGUNIN, Margaret , KAMATH, Rajesh V. , CUFF, Carolyn, A. , ALLEN, Hamish, J.
CPC分类号: C07K16/2887 , A61K39/3955 , A61K45/06 , A61K47/6845 , A61K2039/505 , A61K2039/70 , C07K16/22 , C07K16/241 , C07K16/244 , C07K16/245 , C07K16/247 , C07K16/248 , C07K16/2866 , C07K16/468 , C07K2317/24 , C07K2317/31 , C07K2317/35 , C07K2317/64 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/76 , C07K2317/92 , G01N33/6869 , G01N2333/545 , Y02A50/386 , Y02A50/41 , Y02A50/412
摘要: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
摘要翻译: 本发明涉及工程化的多价和多特异性结合蛋白,制备方法,具体涉及用于预防,诊断和/或治疗疾病的用途。
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公开(公告)号:EP3235509A1
公开(公告)日:2017-10-25
申请号:EP17168290.9
申请日:2010-03-05
申请人: AbbVie Inc.
发明人: HSIEH, Chung-Ming , HUGUNIN, Margaret , MURTAZA, Anwar , McRAE, Bradford L. , KUTSKOVA, Yuliya , MEMMOTT, John E. , PEREZ, Jennifer M. , ZHONG, Suju , TARCSA, Edit , CLABBERS, Anca , WALLACE, Craig , BRYANT, Shaughn H. , LEDDY, Mary R.
IPC分类号: A61K39/395
CPC分类号: C07K16/468 , A61K39/3955 , A61K2039/505 , A61K2039/507 , A61K2300/00 , C07K16/241 , C07K16/244 , C07K2317/21 , C07K2317/31 , C07K2317/50 , C07K2317/565 , C07K2317/64 , C07K2317/76 , C07K2317/92 , Y02A50/386 , Y02A50/41 , Y02A50/412 , Y02A50/466
摘要: Proteins capable of binding human IL-17 and TNF-α are described along with their use in composition and methods for treating, preventing, and diagnosing diseases related to IL- 17 and TNF-α related diseases and for detecting and/or TNF-α in cells, tissues, samples, and compositions.
摘要翻译: 描述了能够结合人IL-17和TNF-α的蛋白质及其在用于治疗,预防和诊断与IL-17和TNF-α相关的疾病有关的疾病以及用于检测和/或TNF-α的组合物和方法中的用途 在细胞,组织,样品和组合物中。
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3.BISPECIFIC IMMUNOBINDERS DIRECTED AGAINST TNF AND IL-17 审中-公开
标题翻译: BISPEZIFISCHE GEGEN TNF UND IL17 GERICHTETE IMMUNBINDER公开(公告)号:EP2771361A1
公开(公告)日:2014-09-03
申请号:EP12783474.5
申请日:2012-10-24
申请人: AbbVie Inc.
发明人: HSIEH, Chung-Ming , PEREZ, Jennifer , BENATUIL, Lorenzo , KUTSKOVA, Yuliya , MEMMOTT, John , ZHONG, Suju , EATON, Lucia , HUGUNIN, Margaret , BRITO, Alyssa , CLABBERS, Anca
IPC分类号: C07K16/24 , C07K16/46 , A61K39/395
CPC分类号: A61K39/3955 , A61K45/06 , A61K2039/505 , C07K16/241 , C07K16/244 , C07K16/468 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/565 , C07K2317/567 , C07K2317/622 , C07K2317/64 , C07K2317/76 , C07K2317/92 , C07K2317/94 , G01N33/5308
摘要: Engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease are provided.
摘要翻译: 提供了工程化的多价和多特异性结合蛋白,制备方法,特别是其用于预防,诊断和/或治疗疾病的用途。
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