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公开(公告)号:EP3066123A1
公开(公告)日:2016-09-14
申请号:EP14803021.6
申请日:2014-11-07
申请人: AbbVie Inc. , Althouse, Heidi , Ananthakrishnan, Shilpa , Coppola, Germano , Ennis, Scott , Hickman, Robert, Keith , Wang, Chen , Yakamavich, Joe
发明人: ALTHOUSE, Heidi , ANANTHAKRISHNAN, Shilpa , COPPOLA, Germano , ENNIS, Scott , HICKMAN, Robert, Keith , WANG, Chen , YAKAMAVICH, Joe
CPC分类号: C07K1/165 , A61K39/395 , C07K1/22 , C07K1/34 , C07K1/36 , C07K16/00 , C07K16/065
摘要: Embodiments of the present invention are directed to high throughput flow through purification of antibodies using mixed mode chromatography.
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公开(公告)号:EP3066121A1
公开(公告)日:2016-09-14
申请号:EP14805732.6
申请日:2014-11-07
申请人: AbbVie Inc. , Althouse, Heidi , Ananthakrishnan, Shilpa , Coppola, Germano , Ennis, Scott , Hickman, Robert, Keith , Wang, Chen , Yakamavich, Joe
发明人: ALTHOUSE, Heidi , ANANTHAKRISHNAN, Shilpa , COPPOLA, Germano , ENNIS, Scott , HICKMAN, Robert, Keith , WANG, Chen , YAKAMAVICH, Joe
CPC分类号: C07K1/165 , A61K39/395 , C07K1/22 , C07K1/34 , C07K1/36 , C07K16/00 , C07K16/065
摘要: Chromatographic methods for isolating and purifying DVD-lgs™ from a sample, wherein the purified DVD-lgs™ have reduced host cell proteins, aggregates, and viruses compared to the sample.
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