公开(公告)号：EP2734619A1

公开(公告)日：2014-05-28

申请号：EP12734892.8

申请日：2012-07-04

申请人： Abbott Biologicals B.V.

发明人： CUI, Yi-Qing ,  WANG, Yiding ,  THUS, Jo ,  VAN 'T HOF, Ron ,  SHAKER, Sabah ,  VAN ROOIJ, Geertje Jacoba

IPC分类号： C12N7/02

CPC分类号： C12N7/00 ,  C12N2760/16151

摘要： The present invention belongs to the field of pharmaceutical industry and relates to a method for the production of viral antigen derived from enveloped virus, comprising the steps of providing a fluid comprising enveloped virus, clarifying the fluid comprising said enveloped virus, reducing the volume of the obtained liquid harvest, solubilizing the enveloped virus, and purifying viral antigen. The present invention further refers to the use of said method for the production of a vaccine preparation.

摘要翻译： 本发明属于制药工业领域，涉及生产包膜病毒的病毒抗原的方法，包括以下步骤：提供包含包膜病毒的流体，澄清包含所述包膜病毒的流体，减少 获得液体收获物，溶解包膜病毒，并纯化病毒抗原。 本发明还涉及所述用于制备疫苗制剂的方法的用途。