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公开(公告)号：EP1140908B1
公开(公告)日：2009-03-04
申请号：EP00902583.4
申请日：2000-01-12
申请人： Abbott GmbH & Co. KG
发明人： STARCK, Dorothea , TREIBER, Hans-Jörg , UNGER, Liliane , NEUMANN-SCHULTZ, Barbara , BLUMBACH, Kai , SCHÖBEL, Dietmar
IPC分类号： C07D403/12 , A61K31/41 , A61P25/16 , A61P25/18 , A61P25/24 , C07D249/12 , C07D413/12
CPC分类号： C07D401/04 , C07D249/12 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/12 , C07D405/06 , C07D409/04 , C07D409/14 , C07D417/04 , C07D417/14 , C07D491/04
摘要： The invention relates to triazole compounds of formula (I), in which R1, R2, A and B have the meanings given in the description. The compounds provided for in the invention have a high affinity for the dopamine-D¿3?-receptor and can therefore be used for the treatment of diseases which respond to the influence of dopamine-D3-ligands.
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公开(公告)号：EP1594861A1
公开(公告)日：2005-11-16
申请号：EP04708353.0
申请日：2004-02-05
申请人： Abbott GmbH & Co. KG
发明人： STARCK, Dorothea , TREIBER, Hans-Jörg , ZIERKE, Thomas , KETTSCHAU, Georg , GENESTE, Hervé , HAUPT, Andreas , UNGER, Liliane , BLUMBACH, Kai , SCHÖBEL, Dietmar , TESCHENDORF, Hans-Jürgen
IPC分类号： C07D403/12 , C07D401/12 , A61K31/41 , A61P25/00
CPC分类号： C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/14 , C07D409/14 , C07D417/14
摘要： The invention relates to triazole compounds of general formula (I), wherein A, B, R1, R2, R3 and R4 have the meaning cited in claim 1. The invention also relates to a pharmaceutical agent containing at least one compound of general formula (I) in addition to the use of the compound (I) for producing a pharmaceutical agent for treating illnesses, responding to the effects of dopamine-D3-receptor antagonists or dopamine-D3-receptor agonists, especially for treating disorders in the central nervous system.
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公开(公告)号：EP1144405B1
公开(公告)日：2009-11-25
申请号：EP00903574.2
申请日：2000-01-12
申请人： Abbott GmbH & Co. KG
发明人： STARCK, Dorothea , TREIBER, Hans-Jörg , UNGER, Liliane , NEUMANN-SCHULTZ, Barbara , BLUMBACH, Kai , SCHÖBEL, Dietmar
IPC分类号： C07D401/12 , C07D401/14 , A61K31/41 , A61P25/16 , A61P25/18 , A61P25/24 , C07D413/14 , C07D417/14 , C07D401/06 , C07D409/14
CPC分类号： C07D401/04 , C07D249/12 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/12 , C07D405/06 , C07D409/04 , C07D409/14 , C07D417/04 , C07D417/14 , C07D491/04
摘要： The invention relates to triazole compounds of formula (I) in which R1, R2, A and B have the meanings given in the description. The compounds provided for in the invention have a high affinity for the dopamine-D¿3?-receptor and are therefore suitable for the treatment of diseases which respond to the influence of dopamine-D3-receptor ligands.
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公开(公告)号：EP1594861B1
公开(公告)日：2008-06-18
申请号：EP04708353.0
申请日：2004-02-05
申请人： Abbott GmbH & Co. KG
发明人： STARCK, Dorothea , TREIBER, Hans-Jörg , ZIERKE, Thomas , KETTSCHAU, Georg , GENESTE, Hervé , HAUPT, Andreas , UNGER, Liliane , BLUMBACH, Kai , SCHÖBEL, Dietmar , TESCHENDORF, Hans-Jürgen
IPC分类号： C07D403/12 , C07D401/12 , A61K31/41 , A61P25/00
CPC分类号： C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/14 , C07D409/14 , C07D417/14
摘要： The invention relates to triazole compounds of general formula (I), wherein A, B, R1, R2, R3 and R4 have the meaning cited in claim 1. The invention also relates to a pharmaceutical agent containing at least one compound of general formula (I) in addition to the use of the compound (I) for producing a pharmaceutical agent for treating illnesses, responding to the effects of dopamine-D3-receptor antagonists or dopamine-D3-receptor agonists, especially for treating disorders in the central nervous system.
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公开(公告)号：EP1140907B1
公开(公告)日：2007-07-11
申请号：EP00901535.5
申请日：2000-01-12
申请人： Abbott GmbH & Co. KG
发明人： STARCK, Dorothea , TREIBER, Hans-Jörg , UNGER, Liliane , NEUMANN-SCHULTZ, Barbara , BLUMBACH, Kai , SCHÖBEL, Dietmar
IPC分类号： C07D403/06 , C07D403/14 , A61K31/41 , A61P25/16 , A61P25/18 , A61P25/24 , C07D403/12
CPC分类号： C07D401/04 , C07D249/12 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/12 , C07D405/06 , C07D409/04 , C07D409/14 , C07D417/04 , C07D417/14 , C07D491/04
摘要： The invention relates to triazole compounds of formula (I), in which R1, R2, A and B have the meanings given in the description. The compounds provided for in the invention have a high affinity for the dopamine-D¿3?-receptor and can therefore be used for the treatment of diseases which respond to the influence of dopamine-D3-ligands.
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