公开(公告)号：EP1023317A1

公开(公告)日：2000-08-02

申请号：EP98953379.9

申请日：1998-10-09

申请人： Abbott Laboratories

发明人： HOCHLOWSKI, Jill, E. ,  SOWIN, Thomas, J. ,  NORBECK, Daniel, W. ,  WADE, Warren, S. ,  WHITTERN, David, N.

IPC分类号： C07K1/04 ,  C07B61/00

CPC分类号： C40B50/16 ,  B01J2219/00576 ,  C07K1/047 ,  C40B99/00

摘要： The present invention relates to coding combinatorial chemical libraries synthesized on a plurality of solid supports by attaching 'tags' that comprise fluorine containing compounds in combinations and/or ratios. The tags can be decoded while attached to the solid support by fluorine nuclear magnetic resonance spectroscopy to follow the reaction history of individual beads, and to determine the particular member of the library that is attached on the bead.