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1.发明公开
公开(公告)号：EP3954457A2
公开(公告)日：2022-02-16
申请号：EP21188480.4
申请日：2015-09-25
发明人： Di Tullio, Katrina Petronilla , Taylor, Jay Kendall , ZHAO, Tian-Xian , Wong, Anjulia Chiu-Yuk , Martin, Glenn Brian , Thibodeau, Isabelle Louisette , Breeze, Steven Roy , Sutrala, Smitha RK , Hong, Eric , Ball, Sheila Diane
摘要： The present invention relates to sample analysis cartridges comprising micro-environment sensors and methods for assaying coagulation in a fluid sample applied to the micro-environment sensors, and in particular, to performing coagulation assays using micro-environment sensors in a point of care sample analysis cartridge. For example, the present invention may be directed to a sample analysis cartridge including an inlet chamber configured to receive a biological sample, and a conduit fluidically connected to the inlet chamber and configured to receive the biological sample from the inlet chamber. The conduit may include a micro-environment prothrombin time (PT) sensor, and a micro-environment activated partial thromboplastin time (aPTT) sensor.
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2.发明公开
公开(公告)号：EP3954457A3
公开(公告)日：2022-05-18
申请号：EP21188480.4
申请日：2015-09-25
发明人： Di Tullio, Katrina Petronilla , Taylor, Jay Kendall , ZHAO, Tian-Xian , Wong, Anjulia Chiu-Yuk , Martin, Glenn Brian , Thibodeau, Isabelle Louisette , Breeze, Steven Roy , Sutrala, Smitha RK , Hong, Eric , Ball, Sheila Diane
摘要： The present invention relates to sample analysis cartridges comprising micro-environment sensors and methods for assaying coagulation in a fluid sample applied to the micro-environment sensors, and in particular, to performing coagulation assays using micro-environment sensors in a point of care sample analysis cartridge. For example, the present invention may be directed to a sample analysis cartridge including an inlet chamber configured to receive a biological sample, and a conduit fluidically connected to the inlet chamber and configured to receive the biological sample from the inlet chamber. The conduit may include a micro-environment prothrombin time (PT) sensor, and a micro-environment activated partial thromboplastin time (aPTT) sensor.
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公开(公告)号：EP3955003A1
公开(公告)日：2022-02-16
申请号：EP21175119.3
申请日：2015-09-25
发明人： ZHAO, Tian-Xian , Wong, Anjulia Chiu-Yuk , Martin, Glenn Brian , Di Tullio, Katrina Petronilla , Thibodeau, Isabelle Louisette , Breeze, Steven Roy , Sutrala, Smitha RK , Hong, Eric , Ball, Sheila Diane
摘要： The present invention relates to analytical testing devices including micro-environment sensors and methods for assaying coagulation in a fluid sample applied to the micro-environment sensors, and in particular, performing one or more types of coagulation assays using one or more micro-environment sensors in a single point of care combined test cartridge. For example, the present invention may be directed to test sensor including at least one transducer coated with a polymer layer. The polymer layer comprises a thrombin-cleavable peptide with a detectable moiety.
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