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公开(公告)号:EP3838893A1
公开(公告)日:2021-06-23
申请号:EP19849476.7
申请日:2019-08-15
发明人: ZHOU, Xinbo , WANG, Yanming , FAN, Shiyong , LI, Song , ZHONG, Wu , XIAO, Junhai , ZHENG, Zhibing , LI, Xingzhou , XIAO, Dian , XIE, Yunde , WANG, Xiaokui , CAO, Ruiyuan
IPC分类号: C07D207/416 , C07D207/46 , C07C323/60 , C07C323/52 , A61K31/4015 , A61K31/337 , C07K5/093 , A61K47/68 , A61P3/00 , A61P7/00 , A61P29/00 , A61P31/00 , A61P35/00 , A61P35/02
摘要: Provided are a linker represented by Formula I or I', an antibody-drug conjugate containing the same, and use of thereof, a pharmaceutical composition comprising the antibody-drug conjugate, and use of the antibody-drug conjugate for treating and/or preventing a disease.
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2.
公开(公告)号:EP3845251A1
公开(公告)日:2021-07-07
申请号:EP19853328.3
申请日:2019-08-28
发明人: ZHOU, Xinbo , WANG, Yanming , LI, Song , ZHONG, Wu , FAN, Shiyong , XIAO, Dian , XIAO, Junhai , ZHENG, Zhibing , LI, Xingzhou , XIE, Yunde , CAO, Ruiyuan , WANG, Xiaokui
摘要: The present application relates to a linker containing arylnitro, an antibody-drug conjugate the linker and use of the linker, as well as a pharmaceutical composition comprising the antibody-drug conjugate and use of the antibody-drug conjugate for treatment and/or prevention of a disease.
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