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1.发明公开
公开(公告)号：EP2591152A1
公开(公告)日：2013-05-15
申请号：EP10761068.5
申请日：2010-09-03
发明人： BHANDARI, Paridhi , DENDUKURI, Dhananjaya , GANAPATHY, Vijayakumar , KANDASWAMY, Srinivasan , LEWIS, Diya
CPC分类号： C07K17/02 , C07K14/435 , D01C3/02 , G01N33/544 , G01N2333/43578 , Y02A50/58
摘要： In one aspect, the invention provides a method for making a hydrophilic-silk composition. The method includes providing at least one strand of silk fiber, treating the silk fiber with an alkaline solution to provide at least one strand of degummed silk fiber, and treating the degummed silk fiber with a treatment solution to provide a hydrophilic-silk composition. The degummed silk fiber or the hydrophilic-silk composition is further immobilized with at least one reagent to make a silk-based diagnostic composition. The invention provides a silk-based diagnostic composition made by the method of the invention, and a diagnostic device that comprises the silk-based diagnostic composition. In another aspect, the invention provides a method of making a diagnostic device. The method includes providing at least one strand of a diagnostic-fiber composition, providing at least one strand of a hydrophobic-fiber composition, inter-weaving the at least one strand of the diagnostic-fiber composition and the at least one strand of the hydrophobic-fiber composition. In one embodiment, the diagnostic-fiber composition and the hydrophobic-fiber composition are both based on silk.
摘要翻译： 在一个方面，本发明提供用于制备亲水性丝组合物的方法。 该方法包括提供丝纤维中的至少一个海滩上，丝处理纤维与在碱性溶液中以提供脱胶丝纤维中的至少一个海滩，并处理所述脱胶丝纤维用处理溶液，以提供亲水性丝组合物。 脱胶丝纤维或亲水性丝组合物进一步与至少一种固定化试剂使一个丝基诊断组合物。 本发明提供了通过本发明的方法制造的丝基诊断组合物，以及一个诊断装置包括没丝基诊断组合物。 在另一个方面，本发明提供制备的诊断装置的方法。 该方法包括提供一个诊断纤维组合物中的至少一个海滩上，提供疏水性纤维组合物中的至少一个海滩，织间诊断纤维组合物的至少一个海滩和疏水性的至少一个海滩 - 纤维组合物。 在一个中，实施方式诊断纤维组合物和所述疏水性纤维的组合物都是基于丝。
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2.发明公开METHODS OF MAKING A DIAGNOSTIC DEVICE BY INTERWEAVING HYDROPHOBIC AND HYDROPHILIC FIBERS, AND DIAGNOSTIC DEVICE THEREFROM 审中-公开一种用于生产诊断设备通过积分疏水和亲水性纤维和诊断及其装置
公开(公告)号：EP2590742A1
公开(公告)日：2013-05-15
申请号：EP10757479.0
申请日：2010-09-03
发明人： BHANDARI, Paridhi , DENDUKURI, Dhananjaya , GANAPATHY, Vijayakumar , KANDASWAMY, Srinivasan , LEWIS, Diya
IPC分类号： B01L3/00
CPC分类号： B01L3/50273 , B01L3/5023 , B01L3/502707 , B01L2200/10 , B01L2200/12 , B01L2300/0864 , B01L2300/0867 , B01L2300/087 , B01L2300/161 , B01L2400/0406 , D03D25/00 , G01N33/5302
摘要： In one aspect, the invention provides a method for making a hydrophilic-silk composition. The method includes providing at least one strand of silk fiber, treating the silk fiber with an alkaline solution to provide at least one strand of degummed silk fiber, and treating the degummed silk fiber with a treatment solution to provide a hydrophilic-silk composition. The degummed silk fiber or the hydrophilic-silk composition is further immobilized with at least one reagent to make a silk-based diagnostic composition. The invention provides a silk-based diagnostic composition made by the method of the invention, and a diagnostic device that comprises the silk- based diagnostic composition. In another aspect, the invention provides a method of making a diagnostic device. The method includes providing at least one strand of a diagnostic-fiber composition, providing at least one strand of a hydrophobic-fiber composition, inter-weaving the at least one strand of the diagnostic-fiber composition and the at least one strand of the hydrophobic-fiber composition. In one embodiment, the diagnostic-fiber composition and the hydrophobic-fiber composition are both based on silk.
摘要翻译： 在一个方面，本发明提供用于制备亲水性丝组合物的方法。 该方法包括提供丝纤维中的至少一个海滩上，丝处理纤维与在碱性溶液中以提供脱胶丝纤维中的至少一个海滩，并处理所述脱胶丝纤维用处理溶液，以提供亲水性丝组合物。 脱胶丝纤维或亲水性丝组合物进一步与至少一种固定化试剂使一个丝基诊断组合物。 本发明提供了通过本发明的方法制造的丝基诊断组合物，以及一个诊断装置包括没丝基诊断组合物。 在另一个方面，本发明提供制备的诊断装置的方法。 该方法包括提供一个诊断纤维组合物中的至少一个海滩上，提供疏水性纤维组合物中的至少一个海滩，织间诊断纤维组合物的至少一个海滩和疏水性的至少一个海滩 - 纤维组合物。 在一个中，实施方式诊断纤维组合物和所述疏水性纤维的组合物都是基于丝。
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