公开(公告)号：EP2925304A1

公开(公告)日：2015-10-07

申请号：EP13859441.1

申请日：2013-11-27

申请人： Acura Pharmaceuticals, Inc.

发明人： BRZECZKO, Albert, W. ,  HOLLENBECK, R., Gary

IPC分类号： A61K9/14 ,  A61K9/48

CPC分类号： A61K47/02 ,  A61K9/2009 ,  A61K9/2027 ,  A61K9/2077 ,  A61K31/5517 ,  A61K47/32

摘要： An abuse deterrent pharmaceutical composition including a pharmaceutically active ingredient; an acid soluble ingredient; and a buffering ingredient; wherein the acid soluble ingredient and the buffering ingredient retard release of the active pharmaceutical ingredient when the composition is ingested in excess of an intended dosage.

公开(公告)号：EP2925304B1

公开(公告)日：2018-09-05

申请号：EP13859441.1

申请日：2013-11-27

申请人： Acura Pharmaceuticals, Inc.

发明人： BRZECZKO, Albert, W. ,  HOLLENBECK, R., Gary

IPC分类号： A61K9/20 ,  A61K9/14 ,  A61K9/48

CPC分类号： A61K47/02 ,  A61K9/2009 ,  A61K9/2027 ,  A61K9/2077 ,  A61K31/5517 ,  A61K47/32

摘要： An abuse deterrent pharmaceutical composition including a pharmaceutically active ingredient; an acid soluble ingredient; and a buffering ingredient; wherein the acid soluble ingredient and the buffering ingredient retard release of the active pharmaceutical ingredient when the composition is ingested in excess of an intended dosage.