公开(公告)号：EP1534344A2

公开(公告)日：2005-06-01

申请号：EP03762001.0

申请日：2003-06-25

申请人： Advanced Bionutrition Corporation ,  Allnutt, Thomas F. C. ,  Kyle, David J.

发明人： ALLNUTT, F.C. Thomas ,  KYLE, David J.

IPC分类号： A61K48/00

CPC分类号： C07K14/005 ,  A61K39/12 ,  A61K39/21 ,  A61K39/292 ,  A61K2039/5254 ,  A61K2039/5256 ,  A61K2039/5258 ,  A61K2039/542 ,  C07K2319/00 ,  C12N7/00 ,  C12N2720/10023 ,  C12N2720/10043 ,  C12N2720/10061 ,  C12N2720/10062 ,  C12N2720/12023 ,  C12N2730/10122 ,  C12N2730/10134 ,  C12N2740/16034 ,  C12N2740/16061 ,  C12N2770/22022 ,  C12N2770/22023 ,  C12N2770/22043 ,  C12N2770/32043 ,  C12N2810/854

摘要： The present invention relates to the display of antigenic or allergenic components along with a tissue-targeting component on viruses or virus-like particles. Capsid protein genes are recombinantly modified to contain the specified components, then expressed within a host organism, such as yeasts, bacteria, or algae, and allowed to spontaneously form active virus particles or virus-like particles. The recombinant complexes (virus or virus-like particle) can then be purified or used in situ as a therapeutic tool for disease or allergy prevention. The expression of multivalent and multifunctional components to increase the immunogenicity of the recombinant complexes, especially on oral administration, is provided.

公开(公告)号：EP1613173A2

公开(公告)日：2006-01-11

申请号：EP04757660.8

申请日：2004-03-19

申请人： Advanced Bionutrition Corporation

发明人： KYLE, David J. ,  HAREL, Moti ,  PIECHOCKI, John

IPC分类号： A23L1/00

CPC分类号： C12N15/8263 ,  C12N15/8266 ,  C12N15/827 ,  C12N15/8289 ,  C12N15/829

摘要： This invention is directed to the composition, method of production, and use of improved edible fish, crustacean, or mollusk products enriched with one or more components that provide health benefits to humans or other animals consuming the product.