公开(公告)号：EP2396289A1

公开(公告)日：2011-12-21

申请号：EP10705933.9

申请日：2010-02-11

申请人： Agency for Science, Technology and Research ,  Mitsui Chemicals, Inc.

发明人： SEAYAD, Abdul Majeed ,  RAMALINGAM, Balamurugan ,  CHAI, Christina ,  NAGATA, Takushi ,  YOSHINAGA, Kazuhiko ,  WADAMOTO, Manabu

IPC分类号： C07B43/08 ,  B01J31/18 ,  B01J31/22

CPC分类号： B01J31/1805 ,  B01J31/2265 ,  B01J2231/341 ,  B01J2531/46 ,  C07B43/08

摘要： The present invention relates to titanium catalysts for synthesis reactions produced by bringing a reaction mixture comprising a titanium alkoxide and a ligand in contact with water, wherein the ligand is represented by the general formula (e): wherein R
1 , R
2 , R
3 , and R
4 are independently a hydrogen atom, an alkyl group, or the like, and (A) represents a group with two or more carbon atoms. The titanium catalysts may be isolated in solid form and may be stored. The invention further relates to a process for cyanation of imines, wherein the process comprises reacting an imine with a cyanating agent in the presence of the titanium catalyst.

公开(公告)号：EP2190851A1

公开(公告)日：2010-06-02

申请号：EP08834037.7

申请日：2008-09-26

申请人： Agency for Science, Technology and Research ,  Mitsui Chemicals, Inc.

发明人： SEAYAD, Abdul Majeed ,  RAMALINGAM, Balamurugan ,  CHAI, Christina ,  NAGATA, Takushi ,  YOSHINAGA, Kazuhiko

IPC分类号： C07F7/28

CPC分类号： C07C253/30 ,  C07B41/02 ,  C07B43/08 ,  C07B53/00 ,  C07C255/19

摘要： The present invention relates to titanium catalysts for asymmetric synthesis reactions produced by bringing a reaction mixture obtained by contacting water and a titanium alkoxide into contact with an optically active ligand represented by the general formula (a), wherein R1, R2, R3, and R4 are independently a hydrogen atom, an alkyl group, or the like, and A* represents a group with two or more carbon atoms having an asymmetric carbon atom or axial asymmetry. The invention further relates to a process for asymmetric cyanation of imines, wherein the process comprises reacting an imine with a cyanating agent in the presence of the titanium catalyst.

公开(公告)号：EP2137197A1

公开(公告)日：2009-12-30

申请号：EP07808949.7

申请日：2007-09-28

申请人： Agency for Science, Technology And Research ,  Mitsui Chemicals, Inc.

发明人： SEAYAD, Abdul, Majeed ,  CHAI, Christina ,  RAMALINGAM, Balamurugan ,  NAGATA, Takushi ,  YOSHINAGA, Kazuhiko

IPC分类号： C07F7/00

CPC分类号： C07C253/30 ,  C07B41/02 ,  C07B43/08 ,  C07B53/00 ,  C07C255/19

摘要： The present invention relates to titanium catalysts for asymmetric synthesis reactions produced by bringing a reaction mixture obtained by contacting water and a titanium alkoxide into contact with an optically active ligand represented by the general formula (a), wherein R1, R2, R3, and R4 are independently a hydrogen atom, an alkyl group, or the like, and A* represents a group with two or more carbon atoms having an asymmetric carbon atom or axial asymmetry. The invention further relates to a process for asymmetric cyanation of imines, wherein the process comprises reacting an imine with a cyanating agent in the presence of the titanium catalyst.

公开(公告)号：EP2294144A1

公开(公告)日：2011-03-16

申请号：EP09746886.2

申请日：2009-05-18

申请人： National University of Singapore ,  Agency for Science, Technology And Research ,  Maritime and Port Authority of Singapore

发明人： TEO, Lay Ming, Serena ,  RITTSCHOF, Daniel ,  JAMESON, Felicity ,  CHAI, Christina ,  CHEN, Chia Lung ,  LEE, Siew Chen, Serina

IPC分类号： C09D5/16 ,  C09D7/12

CPC分类号： C07D295/185 ,  C07D211/46 ,  C07D211/52 ,  C08K5/3435 ,  C09D5/1625 ,  C09D7/63

摘要： The present invention relates to the use of compounds which have the following general formula (I), wherein R1 and R2 are independently selected from optionally substituted aryl, optionally substituted C1 to C12 alkyl and H; and R3 and R4 are independently selected from hydroxy, optionally substituted C1 to C6 alkyl, optionally substituted phenyl and H, in a method of preventing or reducing fouling, particularly in the marine environment. The compounds of the present invention have the considerable advantage of providing the antifouling coating market with an organic alternative to the existing technology which relies heavily on the addition of copper to obtain significant antifouling effects. The compounds we have developed may be used as cheap, easy to prepare additives that do not contain metals and therefore have reduced toxicity in marine environment.

公开(公告)号：EP2294144B1

公开(公告)日：2014-03-05

申请号：EP09746886.2

申请日：2009-05-18

申请人： National University of Singapore ,  Agency for Science, Technology And Research ,  Maritime and Port Authority of Singapore

发明人： TEO, Lay Ming, Serena ,  RITTSCHOF, Daniel ,  JAMESON, Felicity ,  CHAI, Christina ,  CHEN, Chia Lung ,  LEE, Siew Chen, Serina

IPC分类号： C09D5/16 ,  C09D7/12

CPC分类号： C07D295/185 ,  C07D211/46 ,  C07D211/52 ,  C08K5/3435 ,  C09D5/1625 ,  C09D7/63

摘要： The present invention relates to the use of compounds which have the following general formula (I), wherein R1 and R2 are independently selected from optionally substituted aryl, optionally substituted C1 to C12 alkyl and H; and R3 and R4 are independently selected from hydroxy, optionally substituted C1 to C6 alkyl, optionally substituted phenyl and H, in a method of preventing or reducing fouling, particularly in the marine environment. The compounds of the present invention have the considerable advantage of providing the antifouling coating market with an organic alternative to the existing technology which relies heavily on the addition of copper to obtain significant antifouling effects. The compounds we have developed may be used as cheap, easy to prepare additives that do not contain metals and therefore have reduced toxicity in marine environment.