专利检索 ap:("Agensys, Inc.") AND inv:"ETESSAMI, Soudabeh" 第 1 页

1.

发明公开
ANTIBODIES AND MOLECULES DERIVED THEREFROM THAT BIND TO STEAP-1 PROTEINS 有权
标题翻译：抗体和它们的衍生物分子是否涉及STEAP-1蛋白结合

公开(公告)号：EP1742966A2

公开(公告)日：2007-01-17

申请号：EP04750565.6

申请日：2004-04-22

申请人： Agensys, Inc.

发明人： JAKOBOVITS, Aya , ETESSAMI, Soudabeh , CHALLITA-EID, Pia, M. , PEREZ-VILLAR, Juan, J. , MORRISON, Karen, J. , JIA, Xiao-Chi , FARIS, Mary , GUDAS, Jean , RAITANO, Arthur, B.

IPC分类号： C07K16/00

CPC分类号： C07K16/40 , A61K39/39533 , A61K45/06 , A61K47/48607 , A61K47/6861 , A61K51/106 , A61K51/1075 , A61K2039/505 , C07H21/04 , C07K16/3069 , C07K2317/24 , C07K2317/565 , G01N33/6887 , A61K2300/00

摘要： Antibodies and molecules derived therefrom that bind to novel STEAP-1 protein, and variants thereof, are described wherein STEAP-1 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, STEAP-1 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The STEAP-1 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with STEAP-1 can be used in active or passive immunization.

2.

发明授权
ANTIBODIES AND MOLECULES DERIVED THEREFROM THAT BIND TO STEAP-1 PROTEINS 有权
标题翻译：抗体和它们的衍生物分子是否涉及STEAP-1蛋白结合

公开(公告)号：EP1742966B1

公开(公告)日：2013-11-27

申请号：EP04750565.6

申请日：2004-04-22

申请人： Agensys, Inc.

发明人： JAKOBOVITS, Aya , ETESSAMI, Soudabeh , CHALLITA-EID, Pia, M. , PEREZ-VILLAR, Juan, J. , MORRISON, Karen, J. , JIA, Xiao-Chi , FARIS, Mary , GUDAS, Jean , RAITANO, Arthur, B.

IPC分类号： C07K16/30 , A61K39/395

CPC分类号： C07K16/40 , A61K39/39533 , A61K45/06 , A61K47/48607 , A61K47/6861 , A61K51/106 , A61K51/1075 , A61K2039/505 , C07H21/04 , C07K16/3069 , C07K2317/24 , C07K2317/565 , G01N33/6887 , A61K2300/00

摘要： Antibodies and molecules derived therefrom that bind to novel STEAP-1 protein, and variants thereof, are described wherein STEAP-1 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, STEAP-1 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The STEAP-1 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with STEAP-1 can be used in active or passive immunization.