公开(公告)号：EP1635375A3

公开(公告)日：2007-01-10

申请号：EP05003692.0

申请日：2005-02-21

申请人： Agilent Technologies Inc. (a Delaware Corporation)

发明人： Flanagan, Michael J. ,  Loucks, Harvey D., Jr.

IPC分类号： H01J49/04

CPC分类号： H01J49/04 ,  H01J49/107

摘要： The invention provides a multi-inlet sampling device for an ion source. In general, the sampling device contains at least two sample inlet capillaries and a single outlet capillary that are all fluidically connected. A mass spectrometer ion source and a mass spectrometer system containing the multi-inlet sampling device are also provided. The device is readily removed and installed at ambient pressure without venting the mass spectrometer. Also provided by the invention are methods for simultaneously introducing at least two samples into a mass analyzer.

公开(公告)号：EP1635375A2

公开(公告)日：2006-03-15

申请号：EP05003692.0

申请日：2005-02-21

申请人： Agilent Technologies Inc. (a Delaware Corporation)

发明人： Flanagan, Michael J. ,  Loucks, Harvey D., Jr.

IPC分类号： H01J49/04

CPC分类号： H01J49/04 ,  H01J49/107

摘要： The invention provides a multi-inlet sampling device for an ion source. In general, the sampling device contains at least two sample inlet capillaries and a single outlet capillary that are all fluidically connected. A mass spectrometer ion source and a mass spectrometer system containing the multi-inlet sampling device are also provided. The device is readily removed and installed at ambient pressure without venting the mass spectrometer. Also provided by the invention are methods for simultaneously introducing at least two samples into a mass analyzer.

摘要翻译： 本发明提供了一种用于离子源的多入口采样装置。 通常，取样装置包含至少两个样品入口毛细管和一个单独的出口毛细管，其全部流体连接。 还提供了包含多入口采样装置的质谱仪离子源和质谱仪系统。 该装置容易地移除并安装在环境压力下，而不排放质谱仪。 本发明还提供了同时将至少两个样品引入质量分析器的方法。

公开(公告)号：EP1703541A2

公开(公告)日：2006-09-20

申请号：EP06002934.5

申请日：2006-02-14

申请人： AGILENT TECHNOLOGIES, INC. (A Delaware Corporation)

发明人： Goodley, Paul C. ,  Loucks, Jr., Harvey D. ,  Flanagan, Michael J.

IPC分类号： H01J49/10

CPC分类号： H01J49/10

摘要： The present invention provides an apparatus and method for use with a mass spectrometer. The invention provides a mass spectrometer system for non-pneumatic ion production, including a non-pneumatic nanospray ionization source. The nanospray ionization source has a first non-pneumatic ion spray emitter for producing ions; a conduit adjacent to the ion spray emitter, the conduit having an aperture designed for receiving ions from the ion spray emitter; a first electrode for directing the ions from the ion spray emitter toward the aperture of the capillary; and a conduit electrode for directing ions into the conduit; and detector down stream from the capillary for detecting ions produced by the non-pneumatic nanospray ionization source.
The invention also provides a non-pneumatic nanospray ionization source, comprising a first non-pneumatic ion spray emitter for producing ions; a conduit adjacent to the ion spray emitter, the conduit having an aperture designed for receiving ions from the ion spray emitter; a first electrode for directing ions from the ion spray emitter toward the aperture of the conduit and a conduit electrode for directing ions into the conduit.
Also disclosed is a method for producing ions using a nanospray ionization source.

摘要翻译： 本发明提供了一种与质谱仪一起使用的装置和方法。 本发明提供了一种用于非气动离子生产的质谱仪系统，包括非气动纳米喷雾电离源。 纳米喷雾电离源具有用于产生离子的第一非气动离子喷射发射体; 与所述离子喷射发射器相邻的导管，所述导管具有设计成用于从所述离子喷射发射器接收离子的孔; 用于将离子从离子喷射器引导到毛细管的孔的第一电极; 以及用于将离子引导到导管中的导管电极; 并从毛细管下游探测由非气动纳米喷雾电离源产生的离子。 本发明还提供一种非气动纳米喷雾电离源，包括用于产生离子的第一非气动离子喷射发射体; 与所述离子喷射发射器相邻的导管，所述导管具有设计成用于从所述离子喷射发射器接收离子的孔; 用于将离子从离子喷射器引导到导管的孔的第一电极和用于将离子引导到导管中的导管电极。 还公开了使用纳米喷雾电离源产生离子的方法。