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公开(公告)号:EP3184627A1
公开(公告)日:2017-06-28
申请号:EP15833662.8
申请日:2015-08-20
发明人: JIN, Yonghui , HARATA, Ikue , SENDA, Sho , OZAWA, Hiroki , KOBAYASHI, Tsuyoshi , TOGUCHIDA, Junya , IKEYA, Makoto
IPC分类号: C12N5/00 , A61K35/55 , A61K35/56 , A61P19/00 , A61P19/02 , A61P19/04 , A61P43/00 , C12N5/0775
CPC分类号: C12N5/0663 , A61K35/28 , A61K35/55 , A61K35/56 , A61K2035/124 , C12N5/00 , C12N2500/32 , C12N2500/84
摘要: The problem of the present invention is to provide a means that enables conventionally-difficult growth and culture of mesenchymal stem cells for a long period, without using any special apparatus, equipment and the like. The above problem is solved by providing a medium for mesenchymal stem cells in which seven kinds of nonessential amino acids of glycine, alanine, serine, proline, asparagine, aspartic acid and glutamic acid are reduced.
摘要翻译: 本发明的课题在于提供一种不使用特别的装置,设备等,能够长期进行常规难以间充质干细胞的生长培养的手段。 通过提供其中甘氨酸,丙氨酸,丝氨酸,脯氨酸,天冬酰胺,天冬氨酸和谷氨酸的七种非必需氨基酸被还原的间充质干细胞培养基来解决上述问题。