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    PROCESS FOR THE SYNTHESIS OF N-SUBSTITUTED CYCLIC ALKYLENE UREAS
    1.
    发明公开
    PROCESS FOR THE SYNTHESIS OF N-SUBSTITUTED CYCLIC ALKYLENE UREAS 有权
    用于制备N-取代的环状亚烷基

    公开(公告)号：EP2734507A1

    公开(公告)日：2014-05-28

    申请号：EP12743013.0

    申请日：2012-07-19

    申请人： Allnex IP S.à.r.l.

    发明人： GUPTA, Ram ,  KOBYLANSKA, Irina ,  TREASURER, Urvee ,  FLOOD, Lawrence

    IPC分类号： C07D233/34 ,  C07D403/06 ,  A61K31/4166

    CPC分类号： C07D233/36 ,  C07D233/32 ,  C07D233/34

    摘要： The invention relates to a process for the synthesis of N-substituted cyclic alkylene ureas by reacting a multifunctional aliphatic amine A having at least two amino groups which may be primary or secondary, at least one of which is a primary amino group, -NH
    2 , and at least one of which is a secondary amino group, >NH, the other hydrogen group whereof having been substituted by a hydrocarbyl group which in turn may be substituted by a hydroxyl group, or an amino group, or a carboxyl group, or a ketone carbonyl group, or a hydrazide or hydrazone group, or a mercaptan group, and at least one further functional group selected from the group consisting of primary or secondary amino groups and hydroxyl groups, and an aliphatic organic carbonate component C selected from the group consisting of dialkyl carbonates CD and of alkylene carbonates CA.

    PROCESS FOR THE SYNTHESIS OF CYCLIC ALKYLENE UREAS
    3.
    发明公开
    PROCESS FOR THE SYNTHESIS OF CYCLIC ALKYLENE UREAS 有权
    用于生产环状的亚

    公开(公告)号：EP2734506A1

    公开(公告)日：2014-05-28

    申请号：EP12738701.7

    申请日：2012-07-19

    申请人： Allnex IP S.à.r.l.

    发明人： GUPTA, Ram ,  KOBYLANSKA, Irina ,  TREASURER, Urvee ,  FLOOD, Lawrence

    IPC分类号： C07D233/34 ,  A61K31/4166

    CPC分类号： C07D243/04 ,  C07D233/34 ,  C07D239/10

    摘要： The invention relates to a process for the synthesis of cyclic alkylene ureas comprising reacting in the presence of a basic catalyst, a difunctional amine A having two primary amino groups, and an aliphatic organic carbonate component C selected from the group consisting of dialkyl carbonates CD and of alkylene carbonates CA, wherein the ratio of the amount of substance Ji(-NH2) of primary amino groups -NH2 in the difunctional amine A to the sum M(C) of the amount of substance n(CD) of carbonate groups of a dialkyl carbonate CD and the amount of substance n(CA) of carbonate groups in an alkylene carbonate CA, is at least more than 2, and to the product obtained by this process.