专利检索 ap:("Alnylam Pharmaceuticals, Inc." OR "REGENERON PHARMACEUTICALS, INC.") AND inv:"MCININCH, James D." 第 1 页

1.

发明公开
G PROTEIN-COUPLED RECEPTOR 75 (GPR75) IRNA COMPOSITIONS AND METHODS OF USE THEREOF 审中-公开

公开(公告)号：EP4225917A1

公开(公告)日：2023-08-16

申请号：EP21798896.3

申请日：2021-10-04

申请人： Alnylam Pharmaceuticals, Inc. , Regeneron Pharmaceuticals, Inc.

发明人： MCININCH, James D. , BOSTWICK, Bret Lee , CASTORENO, Adam

IPC分类号： C12N15/113 , A61K31/713 , A61P3/06

2.

发明公开
IRNA COMPOSITIONS AND METHODS FOR TARGETING ANGPTL7 审中-实审

公开(公告)号：EP4408438A1

公开(公告)日：2024-08-07

申请号：EP22877649.8

申请日：2022-09-30

申请人： Alnylam Pharmaceuticals, Inc. , REGENERON PHARMACEUTICALS, INC.

发明人： MCININCH, James D. , JADHAV, Vasant R. , PANDYA, Bhaumik A. , CASTELLANOS-RIZALDOS, Elena , CASTORENO, Adam , ROMANO, Carmelo , PATEL, Gaurang , HU, Ying

IPC分类号： A61K31/713 , A61K48/00 , C12N15/113 , A61P27/06

CPC分类号： A61P27/06 , A01K2207/2020130101 , A01K2227/10520130101 , A01K2267/0320130101 , C12N15/1136 , C12N2310/1420130101 , C12N2310/351520130101 , C12N2310/35120130101 , C12N2310/31520130101 , A61K45/06

3.

发明公开
MICROTUBULE ASSOCIATED PROTEIN TAU (MAPT) IRNA AGENT COMPOSITIONS AND METHODS OF USE THEREOF 审中-实审

公开(公告)号：EP4405484A2

公开(公告)日：2024-07-31

申请号：EP22873902.5

申请日：2022-09-23

申请人： Alnylam Pharmaceuticals, Inc.

发明人： FARLEY, Jonathan Edward , SCHLEGEL, Mark K. , MCININCH, James D. , ZUBER, Jeffrey , CASTORENO, Adam , ABBOTT, Stephen , BARRY, Joseph

IPC分类号： C12N15/113 , A61K31/7115 , A61K31/712 , A61K31/7125 , A61K31/713 , A61P25/28

CPC分类号： C12N15/113 , C12N2310/1420130101 , C12N2310/35120130101 , C12N2310/32120130101 , C12N2310/31520130101 , C12N2310/312520130101 , C12N2310/32220130101 , A61K31/7088

4.

发明公开
CELL DEATH-INDUCING DFFA-LIKE EFFECTOR B (CIDEB) IRNA COMPOSITIONS AND METHODS OF USE THEREOF 审中-实审

公开(公告)号：EP4395790A2

公开(公告)日：2024-07-10

申请号：EP22865752.4

申请日：2022-08-31

申请人： Alnylam Pharmaceuticals, Inc.

发明人： ZUBER, Jeffrey , MCININCH, James D. , SCHLEGEL, Mark K. , CASTORENO, Adam , BONDURANT, Lucas , OZA, Dhaval

IPC分类号： A61K31/713 , C12P19/34

CPC分类号： C12N15/1135 , C12N2310/1420130101 , C12N2310/31520130101 , C12N2310/33220130101 , C12N2310/31820130101 , C12N2310/35120130101 , A61K31/713

5.

发明公开
HUNTINGTIN (HTT) IRNA AGENT COMPOSITIONS AND METHODS OF USE THEREOF 审中-公开

公开(公告)号：EP4051795A1

公开(公告)日：2022-09-07

申请号：EP20811833.1

申请日：2020-10-29

申请人： Alnylam Pharmaceuticals, Inc.

发明人： SOUNDARAPANDIAN, Mangala Meenakshi , MCININCH, James D. , BOSTWICK, Bret Lee , SCHLEGEL, Mark K. , CASTORENO, Adam , ZUBER, Jeffrey

IPC分类号： C12N15/113

6.

发明公开
COMPOSITIONS AND METHODS FOR SILENCING CARBONIC ANHYDRASE 2 EXPRESSION 审中-实审

公开(公告)号：EP4347836A2

公开(公告)日：2024-04-10

申请号：EP22812254.5

申请日：2022-05-27

申请人： Alnylam Pharmaceuticals, Inc.

发明人： ZUBER, Jeffrey , MCININCH, James D. , SCHLEGEL, Mark K. , CASTORENO, Adam

IPC分类号： C12N15/113 , A61K31/105 , A61K31/713

7.

发明公开
SIRNA COMPOSITIONS AND METHODS FOR SILENCING GPAM (GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 1, MITOCHONDRIAL) EXPRESSION 审中-公开

公开(公告)号：EP4162033A2

公开(公告)日：2023-04-12

申请号：EP21821828.7

申请日：2021-06-09

申请人： Alnylam Pharmaceuticals, Inc.

发明人： MCININCH, James D. , BONDURANT, Lucas , DEATON, Aimee

IPC分类号： C12N9/10 , C12N15/113 , A61K31/713 , A61K31/7105

8.

发明公开
TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6 (TRAF6) IRNA COMPOSITIONS AND METHODS OF USE THEREOF 审中-公开

公开(公告)号：EP4161532A2

公开(公告)日：2023-04-12

申请号：EP21821397.3

申请日：2021-06-08

申请人： Alnylam Pharmaceuticals, Inc.

发明人： ROGERS, Arlin , MOBLEY, Melissa , MCININCH, James D.

IPC分类号： A61K31/7088 , A61K31/7115 , A61K31/712 , A61K31/7125

9.

发明公开
COMPLEMENT FACTOR B (CFB) IRNA COMPOSITIONS AND METHODS OF USE THEREOF 审中-公开

公开(公告)号：EP4142738A1

公开(公告)日：2023-03-08

申请号：EP21726778.0

申请日：2021-04-29

申请人： Alnylam Pharmaceuticals, Inc.

发明人： MCININCH, James D. , CASTORENO, Adam , SCHLEGEL, Mark K. , FISHILEVICH, Elane , YUCIUS, Kristina , KAITTANIS, Charalambos

IPC分类号： A61K31/713 , C12N15/113 , A61P7/00

10.

发明公开
FC FRAGMENT OF IGG RECEPTOR AND TRANSPORTER (FCGRT) IRNA COMPOSITIONS AND METHODS OF USE THEREOF 审中-公开

公开(公告)号：EP4127173A1

公开(公告)日：2023-02-08

申请号：EP21776217.8

申请日：2021-03-26

申请人： Alnylam Pharmaceuticals, Inc.

发明人： DEATON, Aimee , PARKER, Margaret , NOETZLI, Leila , MCININCH, James D.

IPC分类号： C12N15/113