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公开(公告)号：EP1641792A1
公开(公告)日：2006-04-05
申请号：EP04741932.0
申请日：2004-06-30
申请人： ALTANA Pharma AG
发明人： VENNEMANN, Matthias , BAER, Thomas , BRAUNGER, Juergen , MAIER, Thomas , GRAEDLER, Ulrich , GIMMNICH, Petra , QUINTINI, Gianluca , CIAPETTI, Paola , CONTRERAS, Jean-Marie , WERMUTH, Camille Georges
IPC分类号： C07D471/04 , A61K31/4745 , A61P25/00 , A61P15/00 , A61P3/10
CPC分类号： C07D471/04 , A61K31/4745
摘要： The invention relates to novel pyrrolodihydroisoquinoline derivatives, which are efficacious inhibitors of PDE10.
摘要翻译： 本发明涉及新的吡咯并二氢异喹啉衍生物，其是PDE10的有效抑制剂。
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2.发明公开BENZOTHIENOPYRIDINES FOR USE AS INHIBITORS OF EG5 KINESIN 有权BENZOTHIENOPYRIDINE FOR USE作为抑制剂的Eg5驱动蛋白
公开(公告)号：EP1781667A1
公开(公告)日：2007-05-09
申请号：EP05777861.5
申请日：2005-08-17
申请人： Altana Pharma AG
发明人： VENNEMANN, Matthias , BAER, Thomas , GROEGOR, Gudrun , BRAUNGER, Juergen , GIMMNICH, Petra , MAIER, Thomas , ROTHFELS, Heike
IPC分类号： C07D495/14 , A61K31/437 , A61P35/00 , C07D471/14
CPC分类号： C07D471/14 , C07D495/14
摘要： Compounds of a certain formula I, in which R1, R2, R3, R4 and X have the meanings indicated in the description, are novel effective compounds with Eg5 inhibitory, anti-proliferative and/or apoptosis inducing activity.
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3.发明公开NOVEL PYRROLODIHYDROISOQUINOLINES USEFUL IN THE TREATMENT OF CANCER 审中-公开新的用于癌症SUITABLE PYRROLODIHYDROISOCHINOLINE的治疗
公开(公告)号：EP1641794A1
公开(公告)日：2006-04-05
申请号：EP04766106.1
申请日：2004-06-30
申请人： ALTANA Pharma AG
发明人： VENNEMANN, Matthias , BAER, Thomas , BRAUNGER, Juergen , GEKELER, Volker , GIMMNICH, Petra , CONTRERAS, Jean-Marie , CIAPETTI, Paola , WERMUTH, Camille Georges
IPC分类号： C07D471/04 , A61K31/4745 , A61P25/00 , A61P35/00
CPC分类号： C07D471/04 , A61K31/4745
摘要： The invention relates to novel pyrrolodihydroisoquinoline derivatives, which are efficacious inhibitors of cellular (hyper)proliferation and/or inducers of apoptosis in cancer cells.
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