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公开(公告)号：EP1140281B1
公开(公告)日：2005-02-16
申请号：EP99963088.2
申请日：1999-12-15
申请人： Alza Corporation
IPC分类号： A61N1/30
CPC分类号： A61N1/0448
摘要： The present invention relates to hydratable drug reservoir films for electrotransport drug delivery devices and to electrotransport drug delivery systems containing the hydratable drug reservoirs and to methods for manufacturing and using such systems. The hydratable reservoir films according to this invention are easily manufacturable and rapidly imbibe water and/or drug solution with good water retention and stability.
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公开(公告)号：EP1140281A1
公开(公告)日：2001-10-10
申请号：EP99963088.2
申请日：1999-12-15
申请人： Alza Corporation
IPC分类号： A61N1/30
CPC分类号： A61N1/0448
摘要： The present invention relates to hydratable drug reservoir films for electrotransport drug delivery devices and to electrotransport drug delivery systems containing the hydratable drug reservoirs and to methods for manufacturing and using such systems. The hydratable reservoir films according to this invention are easily manufacturable and rapidly imbibe water and/or drug solution with good water retention and stability.
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3.发明公开TRANSDERMAL DRUG DELIVERY DEVICES COMPRISING A POLYURETHANE DRUG RESERVOIR 有权经皮装置用于药品监督管理局与聚氨酯ACTIVE水库
公开(公告)号：EP1169025A2
公开(公告)日：2002-01-09
申请号：EP00918530.7
申请日：2000-03-31
申请人： Alza Corporation
CPC分类号： A61K9/7069 , A61K9/7084 , A61K47/34
摘要： The present invention relates to the field of transdermal drug delivery. More specifically, the present invention relates to drug reservoir materials for use in transdermal drug delivery devices. The drug reservoirs of the present invention comprise a polyurethane polymer which can be processed at temperatures below those which cause degradation of temperature sensitive drugs and/or excipients. The present invention is also directed to tailoring the release characteristics of the polyurethane material to accommodate a range of suitable drugs to be delivered from the transdermal drug delivery device and/or provide a range of delivery rates for a particular drug.
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4.发明公开
公开(公告)号：EP1037667A1
公开(公告)日：2000-09-27
申请号：EP98959589.7
申请日：1998-12-01
申请人： ALZA CORPORATION
IPC分类号： A61K47/32
CPC分类号： A61K9/0009 , A61K9/0014 , A61K47/32 , Y10S514/944
摘要： Pharmaceutical hydrogel formulations containing polyvinyl alcohol are provided. The formulations may serve as drug reservoirs in electrotransport drug delivery systems (10) or passive transdermal systems, or they may be used in a variety of other types of dosage forms, e.g., capsules, suppositories, aerosols, and the like. With these formulations, there is virtually no syneresis encountered upon long term storage, an advantage that derives from selecting the quantity of polyvinyl alcohol in the gel to correspond to the polymer's degree of hydrolysis.
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公开(公告)号：EP1381352B1
公开(公告)日：2007-06-13
申请号：EP02715112.5
申请日：2002-03-15
申请人： Alza Corporation
发明人： VENKATRAMAN, Subramanian, S. , LI, Shaoling , GALE, Robert, M. , STEPIC, Jane , VAN OSDOL, William, W.
IPC分类号： A61K9/70 , A61K31/4468
CPC分类号： A61K31/4468 , A61K9/0014 , A61K9/703 , A61K9/7038 , A61K9/7061 , A61K9/7084 , A61K31/4535 , A61K47/14 , A61K47/22 , A61K47/32 , A61K47/34
摘要： A method and a non-rate controlled, monolithic, subsaturated patch for transdermally administering fentanyl and analogs thereof, for analgetic purposes, to a subject through skin over an extended period of time are disclosed.
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6.发明授权TRANSDERMAL DRUG DELIVERY DEVICES COMPRISING A POLYURETHANE DRUG RESERVOIR 有权经皮装置用于药品监督管理局与聚氨酯ACTIVE水库
公开(公告)号：EP1169025B1
公开(公告)日：2005-08-24
申请号：EP00918530.7
申请日：2000-03-31
申请人： ALZA CORPORATION
CPC分类号： A61K9/7069 , A61K9/7084 , A61K47/34
摘要： The present invention relates to the field of transdermal drug delivery. More specifically, the present invention relates to drug reservoir materials for use in transdermal drug delivery devices. The drug reservoirs of the present invention comprise a polyurethane polymer which can be processed at temperatures below those which cause degradation of temperature sensitive drugs and/or excipients. The present invention is also directed to tailoring the release characteristics of the polyurethane material to accommodate a range of suitable drugs to be delivered from the transdermal drug delivery device and/or provide a range of delivery rates for a particular drug.
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7.发明授权
公开(公告)号：EP1037667B1
公开(公告)日：2004-05-12
申请号：EP98959589.7
申请日：1998-12-01
申请人： ALZA CORPORATION
IPC分类号： A61K47/32
CPC分类号： A61K9/0009 , A61K9/0014 , A61K47/32 , Y10S514/944
摘要： Pharmaceutical hydrogel formulations containing polyvinyl alcohol are provided. The formulations may serve as drug reservoirs in electrotransport drug delivery systems (10) or passive transdermal systems, or they may be used in a variety of other types of dosage forms, e.g., capsules, suppositories, aerosols, and the like. With these formulations, there is virtually no syneresis encountered upon long term storage, an advantage that derives from selecting the quantity of polyvinyl alcohol in the gel to correspond to the polymer's degree of hydrolysis.
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公开(公告)号：EP1381352A1
公开(公告)日：2004-01-21
申请号：EP02715112.5
申请日：2002-03-15
申请人： Alza Corporation
发明人： VENKATRAMAN, Subramanian, S. , LI, Shaoling , GALE, Robert, M. , STEPIC, Jane , VAN OSDOL, William, W.
IPC分类号： A61K9/70 , A61K31/4468
CPC分类号： A61K31/4468 , A61K9/0014 , A61K9/703 , A61K9/7038 , A61K9/7061 , A61K9/7084 , A61K31/4535 , A61K47/14 , A61K47/22 , A61K47/32 , A61K47/34
摘要： A method and a non-rate controlled, monolithic, subsaturated patch for transdermally administering fentanyl and analogs thereof, for analgetic purposes, to a subject through skin over an extended period of time are disclosed.
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