公开(公告)号：EP1805219A1

公开(公告)日：2007-07-11

申请号：EP05823196.0

申请日：2005-10-19

申请人： Amgen, Inc

发明人： OLINER, Jonathon, Daniel ,  GRAHAM, Kevin

IPC分类号： C07K16/22 ,  C12N15/13 ,  C07K16/46 ,  C12P21/08 ,  C12N15/20 ,  A61K39/385 ,  A61K39/395 ,  A61P35/00 ,  A61P9/00 ,  G01N33/68 ,  G01N33/577

CPC分类号： C07K16/22 ,  A61K2039/505 ,  C07K2317/21 ,  C07K2317/56 ,  C07K2317/73 ,  C07K2317/76

摘要： Disclosed are specific binding agents, such as fully human antibodies, that bind to angiopoietin-2. Also disclosed are heavy chain fragments, light chain fragments, and CDRs of the antibodies, as well as methods of making and using the antibodies.