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公开(公告)号：EP2366715A3
公开(公告)日：2011-11-02
申请号：EP11156478.7
申请日：2006-11-13
申请人： Amgen Inc.
IPC分类号： C07K16/28 , C07K19/00 , C07K14/635 , A61K39/395 , A61P19/10 , A01K67/027 , C07K14/705
CPC分类号： C07K16/241 , A01K67/0278 , A01K2207/15 , A01K2217/00 , A01K2227/105 , A01K2267/03 , A61K2039/505 , C07K14/635 , C07K14/70575 , C07K16/2875 , C07K2317/21 , C07K2317/76 , C07K2319/00
摘要： Chimeric molecules comprising receptor activator of NF-κB ligand (RANKL) antibodies and parathyroid hormone/parathyroid hormone-related protein (PTH/PTHrP) peptides are described. Compositions and methods for the treatment of bone diseases are also described.
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公开(公告)号：EP2816060A1
公开(公告)日：2014-12-24
申请号：EP14166902.8
申请日：2006-11-13
申请人： Amgen Inc.
IPC分类号： C07K16/28 , C07K19/00 , C07K14/635 , A61K39/395 , A61P19/10 , A01K67/027 , C07K14/705
CPC分类号： C07K16/241 , A01K67/0278 , A01K2207/15 , A01K2217/00 , A01K2227/105 , A01K2267/03 , A61K2039/505 , C07K14/635 , C07K14/70575 , C07K16/2875 , C07K2317/21 , C07K2317/76 , C07K2319/00
摘要： Chimeric molecules comprising receptor activator of NF-κB ligand (RANKL) antibodies and parathyroid hormone/parathyroid hormone-related protein (PTH/PTHrP) peptides are described. Compositions and methods for the treatment of bone diseases are also described.
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3.发明公开
公开(公告)号：EP2366715A2
公开(公告)日：2011-09-21
申请号：EP11156478.7
申请日：2006-11-13
申请人： Amgen Inc.
IPC分类号： C07K16/28 , C07K19/00 , C07K14/635 , A61K39/395 , A61P19/10 , A01K67/027 , C07K14/705
CPC分类号： C07K16/241 , A01K67/0278 , A01K2207/15 , A01K2217/00 , A01K2227/105 , A01K2267/03 , A61K2039/505 , C07K14/635 , C07K14/70575 , C07K16/2875 , C07K2317/21 , C07K2317/76 , C07K2319/00
摘要： Chimeric molecules comprising receptor activator of NF-κB ligand (RANKL) antibodies and parathyroid hormone/parathyroid hormone-related protein (PTH/PTHrP) peptides are described. Compositions and methods for the treatment of bone diseases are also described.
摘要翻译： 描述了包含NF-ºB配体（RANKL）抗体和甲状旁腺激素/甲状旁腺激素相关蛋白（PTH / PTHrP）肽的受体激活剂的嵌合分子。 还描述了用于治疗骨疾病的组合物和方法。
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