专利检索 ap:("Amgen Inc.") AND inv:"MUNRO, Trent, P." 第 1 页

1.

发明公开
DIRECT SELECTION OF CELLS EXPRESSING HIGH LEVELS OF HETEROMERIC PROTEINS USING GLUTAMINE SYNTHETASE INTRAGENIC COMPLEMENTATION VECTORS 审中-公开

公开(公告)号：EP4067493A1

公开(公告)日：2022-10-05

申请号：EP22159835.2

申请日：2017-05-11

申请人： Amgen Inc.

发明人： MUNRO, Trent, P. , AGRAWAL, Neeraj, Jagdish , DARIS, Kristine, M.

IPC分类号： C12N15/65 , C12N15/67

摘要： This invention relates to the general field of recombinant expression of polypeptides in animal cell culture. More specifically, the invention concerns improved selection of cells transfected with recombinantly engineered vectors designed to express polypeptides, in particular heteromultimeric polypeptides.