公开(公告)号：EP4202044A2

公开(公告)日：2023-06-28

申请号：EP22211393.8

申请日：2022-12-05

申请人： Amicogen, Inc.

发明人： PIAO, Zhe ,  WANG, Eun Seon ,  LI, Hong Xian ,  LEE, Mi Kyoung ,  SON, Ah Reum ,  LIM, Su Jin

IPC分类号： C12N9/80 ,  C12P35/06

摘要： Disclosed herein are a polypeptide having cephalosporin C(CPC) acylase activity and a use thereof. More specifically, a mutant CPC acylase comprising a point mutation introduced thereinto, thereby exhibiting improved enzymatic activity and/or stability, and a use of the mutant CPC acylase for producing 7-aminocephalosporanic acid (7-ACA), are provided.

公开(公告)号：EP4202044A3

公开(公告)日：2023-08-23

申请号：EP22211393.8

申请日：2022-12-05

申请人： Amicogen, Inc.

发明人： PIAO, Zhe ,  WANG, Eun Seon ,  LI, Hong Xian ,  LEE, Mi Kyoung ,  SON, Ah Reum ,  LIM, Su Jin

IPC分类号： C12N9/80 ,  C12P35/06

摘要： Disclosed herein are a polypeptide having cephalosporin C(CPC) acylase activity and a use thereof. More specifically, a mutant CPC acylase comprising a point mutation introduced thereinto, thereby exhibiting improved enzymatic activity and/or stability, and a use of the mutant CPC acylase for producing 7-aminocephalosporanic acid (7-ACA), are provided.