-
1.发明公开
公开(公告)号：EP2874648A1
公开(公告)日：2015-05-27
申请号：EP13820417.7
申请日：2013-07-16
CPC分类号： A61K38/47 , A61K31/445 , C12N9/2465 , C12Y302/01022 , A61K2300/00
摘要： The present application provides for compositions comprising α-galactosidase A in combination with an active site-specific chaperone for the α-galactosidase A, and methods for treating Fabry disease in a subject in need thereof, that includes a method of administering to the subject such compositions. The present application also provides methods for increasing the in vitro and in vivo stability of an α-galactosidase A enzyme formulation.
-
公开(公告)号：EP2683382B1
公开(公告)日：2020-04-22
申请号：EP12758017.3
申请日：2012-03-08
IPC分类号： A61K31/445 , A61K38/47 , A61P3/00
-
公开(公告)号：EP2844279A1
公开(公告)日：2015-03-11
申请号：EP13785028.5
申请日：2013-05-02
IPC分类号： A61K38/47
CPC分类号： A61K38/47 , A61K31/445 , C12Y302/0102 , A61K2300/00
摘要： The presently disclosed subject matter provides a dosing regimen and administration schedule for the use of 1 -deoxynojirimycin and enzyme replacement therapy for the treatment of Pompe disease. The presently disclosed subject matter further provides a dosing regimen and administration schedule for the use of 1- deoxynojirimycin hydrochloride and alglucosidase alfa for the treatment of Pompe disease.
摘要翻译： 本发明公开的主题提供了使用1-脱氧野ri霉素和酶替代疗法治疗庞皮病的给药方案和给药方案。 目前公开的主题进一步提供了使用1-脱氧野ri霉素盐酸盐和葡糖苷酶α用于治疗庞皮病的给药方案和给药方案。
-
公开(公告)号：EP2844279B1
公开(公告)日：2020-12-09
申请号：EP13785028.5
申请日：2013-05-02
IPC分类号： A61K38/47 , A61K31/445 , A61P3/00
-
5.发明公开HIGH CONCENTRATION ALPHA-GLUCOSIDASE COMPOSITIONS FOR THE TREATMENT OF POMPE DISEASE 审中-公开用于治疗蓬珀病高浓度α-葡萄糖苷酶的组合物
公开(公告)号：EP2823043A1
公开(公告)日：2015-01-14
申请号：EP13757576.7
申请日：2013-03-07
IPC分类号： C12N9/40 , C07D211/06 , A61K31/58 , C12N9/99
CPC分类号： A61K38/47 , A61K9/0019 , A61K31/445 , A61K31/7008 , A61K47/22 , C12N9/2408 , C12N9/96 , C12Y302/0102 , A61K2300/00
摘要： The present application provides for compositions comprising high concentrations of acid a-glucosidase in combination with an active site-specific chaperone for the acid α-glucosidase, and methods for treating Pompe disease in a subject in need thereof, that includes a method of administering to the subject such compositions. The present application also provides methods for increasing the in vitro and in vivo stability of an acid α-glucosidase enzyme formulation.
-
公开(公告)号：EP2683382A2
公开(公告)日：2014-01-15
申请号：EP12758017.3
申请日：2012-03-08
IPC分类号： A61K31/445
CPC分类号： A61K47/22 , A61K31/445 , A61K38/47 , A61K2300/00
摘要： The presently disclosed subject matter provides a dosing regimen and administration schedule for the use of 1-deoxygalactonojirimycin and enzyme replacement therapy for the treatment of Fabry disease. The presently disclosed subject matter further provides a dosing regimen and administration schedule for the use of migalastat hydrochloride and agalsidase for the treatment of Fabry disease.
-
-
-
-
-
搜索结果
6 条记录 (耗时 0.015 秒)
