专利检索 ap:("Amunix Operating Inc.") AND inv:"ALTERS, Susan E." 第 1 页

1.

发明公开
BINDING FUSION PROTEINS, BINDING FUSION PROTEIN-DRUG CONJUGATES, XTEN-DRUG CONJUGATES AND METHODS OF MAKING AND USING SAME 审中-公开
标题翻译：结合蛋白融合，融合蛋白结合药物结合物，XTEN偶联药物和方法的生产和使用

公开(公告)号：EP2552967A2

公开(公告)日：2013-02-06

申请号：EP11763532.6

申请日：2011-04-01

申请人： Amunix Operating Inc.

发明人： SCHELLENBERGER, Volker , SILVERMAN, Joshua , WANG, Chia-wei , SPINK, Benjamin , STEMMER, Willem, P. , ALTERS, Susan E.

IPC分类号： C07K19/00

CPC分类号： C07K16/28 , C07K2317/622 , C07K2317/90 , C07K2319/01

摘要： The present invention relates to binding fusion protein compositions comprising targeting moieties linked to extended recombinant polypeptide (XTEN), binding fusion protein-drug conjugate compositions, and XTEN-drug conjugate compositions, isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of diseases, disorders, and conditions.