公开(公告)号：EP3466412A1

公开(公告)日：2019-04-10

申请号：EP18183805.3

申请日：2005-04-15

申请人： Amylin Pharmaceuticals, LLC ,  Alkermes Pharma Ireland Limited

发明人： FINEMAN, Mark ,  LOKENSGARD, David ,  WRIGHT, Steven ,  ONG, John ,  KUMAR, Rajesh ,  RICKEY, Michael ,  SMITH, Christine ,  HOTZ, Joyce ,  CHRISTENSON, Troy ,  YEOH, Thean ,  COSTANTINO, Henry

IPC分类号： A61K9/16 ,  A61K38/22 ,  A61K38/26 ,  A61K47/26 ,  A61K47/38

摘要： This invention relates to compositions for the sustained release of biologically active polypeptides, and methods of forming and using said compositions, for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein, a biologically active polypeptide and a sugar.

公开(公告)号：EP2303313B1

公开(公告)日：2015-10-28

申请号：EP09751513.4

申请日：2009-05-20

申请人： Amylin Pharmaceuticals, LLC ,  AstraZeneca Pharmaceuticals LP

发明人： FINEMAN, Mark ,  MACCONELL, Leigh ,  TAYLOR, Kristin

IPC分类号： A61K38/22 ,  A61K38/26 ,  A61P3/06 ,  A61P9/10

CPC分类号： A61K38/179 ,  A61K9/5031 ,  A61K38/2278 ,  A61K38/26 ,  A61K47/34

公开(公告)号：EP1971362B1

公开(公告)日：2014-12-03

申请号：EP06801867.0

申请日：2006-08-18

申请人： Amylin Pharmaceuticals, LLC ,  AstraZeneca Pharmaceuticals LP

发明人： FINEMAN, Mark ,  MACCONELL, Leigh ,  TAYLOR, Kristin

IPC分类号： A61K38/26 ,  A61K9/00 ,  A61P3/10 ,  A61P3/04

CPC分类号： A61K38/26 ,  A61K9/0019 ,  A61K45/06 ,  A61K47/26 ,  A61K47/34 ,  C07K14/46

摘要： Methods for reducing body weight, altering body composition, treating diabetes, reducing HbA 1c and reducing average daily blood glucose by the use of exendins, exendin agonists or exendin analog agonists are provided.