公开(公告)号：EP4390391A1

公开(公告)日：2024-06-26

申请号：EP23158874.0

申请日：2023-04-11

申请人： Ares Trading S.A.

发明人： SATWEKAR, Abhijeet ,  PANDA, Anubhab ,  NANDULA, Phani ,  SRIPADA, Sriharsha ,  GOVINDARAJ, Ramachandiran

IPC分类号： G01N30/86 ,  G01N30/88

CPC分类号： G01N30/8624 ,  G01N30/88

摘要： Provided herein are solutions to improve peak integration for example chromatographic processes using a method which includes elements of artificial intelligence to process the integration of peaks in the chromatographic profiles, as generated from the analytical assays used in the quality testing of therapeutic products. The method of the present invention in chromatographic peak integrations develops a solution for enabling digitalization within the areas of real-time release testing, automated quality control, process analytical technologies, and continuous manufacturing.

公开(公告)号：EP4390390A1

公开(公告)日：2024-06-26

申请号：EP22214727.4

申请日：2022-12-19

申请人： Ares Trading S.A.

发明人： SATWEKAR, Abhijeet ,  PANDA, Anubhab ,  NANDULA, Phani ,  SRIPADA, Sriharsha ,  GOVINDARAJ, Ramachandiran

IPC分类号： G01N30/86 ,  G01N30/88

CPC分类号： G01N30/8624 ,  G01N30/88

摘要： Provided herein are solutions to improve peak integration for example chromatographic processes using a method which includes elements of artificial intelligence to process the integration of peaks in the chromatographic profiles, as generated from the analytical assays used in the quality testing of therapeutic products. The method of the present invention in chromatographic peak integrations develops a solution for enabling digitalization within the areas of real-time release testing, automated quality control, process analytical technologies, and continuous manufacturing.

公开(公告)号：EP4314835A1

公开(公告)日：2024-02-07

申请号：EP22716922.4

申请日：2022-03-21

申请人： Ares Trading S.A.

发明人： MASTRANGELI, Renato ,  SATWEKAR, Abhijeet

IPC分类号： G01N33/68 ,  C12P21/00

公开(公告)号：EP4063866A1

公开(公告)日：2022-09-28

申请号：EP21165362.1

申请日：2021-03-26

申请人： Ares Trading S.A.

发明人： MASTRANGELI, Renato ,  SATWEKAR, Abhijeet

IPC分类号： G01N33/68 ,  C12P21/00

摘要： The glycosylation profile of a biologic molecule describes important aspects of such biologic molecule. The characterization of the glycosylation profile of a biologic molecule is an important part of the critical quality attributes in the manufacturing and analytical processes for biologic molecules. As such described herein are methods to determine and characterize the glycosylation profile of a biologic molecule. In particular, the method uses one or more indices to describe the glycosylation profile as a finger-print of such biologic molecule.