公开(公告)号：EP1720552A2

公开(公告)日：2006-11-15

申请号：EP05724535.9

申请日：2005-03-04

申请人： Arizona Board of Regents, acting for and on behalf of Arizona State University ,  SUN HEALTH RESEARCH INSTITUTE

发明人： CHANG, Yung ,  LORTON, Dianne ,  LUBAHN, Cheri ,  PETTIT, George, R. ,  WILSON, David ,  ANANIEVA, Olga

IPC分类号： A61K31/4741 ,  A61K31/675 ,  A61P1/00 ,  A61P1/02 ,  A61P9/10 ,  A61P11/06 ,  A61P11/00 ,  A61P17/06 ,  A61P19/02 ,  A61P19/10 ,  A61P21/00 ,  A61P29/00 ,  A61P37/02

CPC分类号： A61K31/4741 ,  A61K31/675

摘要： The present invention provides methods for treating inflammatory conditions, rheumatoid diseases, autoimmune conditions, and conditions associated with bone loss, comprising administering to a subject with an inflammatory condition an amount effective to treat the condition of a compound selected from the group consisting of narcistatin, pancratistatin, pancratistatin-7' phosphate and pancratistatin-3',4' cyclic phosphate, or pharmaceutically acceptable salts thereof.