专利检索 ap:("Asahi Kasei Pharma Corporation") AND inv:"MITOME Yoshiro" 第 1 页

1.

发明授权
FREEZE-DRIED PREPARATION CONTAINING HIGH-PURITY PTH AND METHOD FOR PRODUCING SAME 有权

公开(公告)号：EP2719393B1

公开(公告)日：2020-10-21

申请号：EP12796142.3

申请日：2012-05-31

申请人： Asahi Kasei Pharma Corporation

发明人： NISHIO Fumihide , MAEJIMA Takuji , MITOME Yoshiro

IPC分类号： A61K38/22 , A61K9/19 , C07K14/635 , F26B5/06 , G01N30/88 , G01N33/68 , A61P19/10 , A61K38/29

2.

发明公开
FREEZE-DRIED PREPARATION CONTAINING HIGH-PURITY PTH AND METHOD FOR PRODUCING SAME 审中-公开
标题翻译：随着对生产高纯度PTH和过程冻干制剂

公开(公告)号：EP2719393A1

公开(公告)日：2014-04-16

申请号：EP12796142.3

申请日：2012-05-31

申请人： Asahi Kasei Pharma Corporation

发明人： NISHIO Fumihide , MAEJIMA Takuji , MITOME Yoshiro

IPC分类号： A61K38/22 , A61K9/19 , C07K14/635 , F26B5/06 , G01N30/88 , G01N33/68 , A61P19/10

摘要： [Problem] Provided is a freeze-dried preparation containing high-purity PTH peptide and a method for the production thereof. Also provided is a test method for PTH analogs to confirm the purity of a freeze-dried preparation containing PTH peptide, and the like.
[Solution] In the present invention, the presence of PTH analogs produced during the manufacturing process of a freeze-dried preparation containing PTH peptide was confirmed. The production of these PTH analogs was also discovered to be markedly prevented or reduced by controlling exposure of the solution containing PTH peptide and the like to air environments within a pharmaceutical production facility.