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公开(公告)号：EP2563775B1
公开(公告)日：2017-01-04
申请号：EP11724710.6
申请日：2011-04-28
发明人： SAXTY, Gordon , MURRAY, Christopher William , BERDINI, Valerio , BESONG, Gilbert Ebai , HAMLETT, Christopher Charles Frederick , JOHNSON, Christopher Norbert , WOODHEAD, Steven John , READER, Michael , REES, David Charles , MEVELLEC, Laurence Anne , ANGIBAUD, Patrick René , FREYNE, Eddy Jean Edgard , GOVAERTS, Tom Cornelis Hortense , WEERTS, Johan Erwin Edmond , PERERA, Timothy Pietro Suren , GILISSEN, Ronaldus Arnodus Hendrika Joseph , WROBLOWSKI, Berthold , LACRAMPE, Jean Fernand Armand , PAPANIKOS, Alexandra , QUEROLLE, Olivier Alexis Georges , PASQUIER, Elisabeth Thérèse Jeanne , PILATTE, Isabelle Noëlle Constance , BONNET, Pascal Ghislain André , EMBRECHTS, Werner Constant Johan , AKKARI, Rhalid , MEERPOEL, Lieven
IPC分类号： C07D403/04 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D487/08 , A61K31/498 , A61P35/00
CPC分类号： C07D403/04 , A61K31/498 , A61K31/5377 , A61K45/06 , C07D401/14 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D487/08 , C07D491/113 , C07F9/6524
摘要： The invention relates to new quinoxaline derivative compounds, to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
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公开(公告)号：EP3178818A1
公开(公告)日：2017-06-14
申请号：EP16207610.3
申请日：2011-04-28
发明人： SAXTY, Gordon , MURRAY, Christopher William , BERDINI, Valerio , BESONG, Gilbert Ebai , HAMLETT, Christopher Charles Frederick , JOHNSON, Christopher Norbert , WOODHEAD, Steven John , READER, Michael , REES, David Charles , MEVELLEC, Laurence Anne , ANGIBAUD, Patrick René , FREYNE, Eddy Jean Edgard , GOVAERTS, Tom Cornelis Hortense , WEERTS, Johan Erwin Edmond , PERERA, Timothy Pietro Suren , GILISSEN, Ronaldus Arnodus Hendrika Joseph , WROBLOWSKI, Berthold , LACRAMPE, Jean Fernand Armand , PAPANIKOS, Alexandra , QUEROLLE, Olivier Alexis Georges , PASQUIER, Elisabeth Thérèse Jeanne , PILATTE, Isabelle Noëlle Constance , BONNET, Pascal Ghislain André , EMBRECHTS, Werner Constant Johan , AKKARI, Rhalid , MEERPOEL, Lieven
IPC分类号： C07D403/04 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D487/08 , A61K31/498 , A61P35/00
CPC分类号： C07D403/04 , A61K31/498 , A61K31/5377 , A61K45/06 , C07D401/14 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D487/08 , C07D491/113 , C07F9/6524
摘要： The invention relates to new quinoxaline derivative compounds, to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
摘要翻译： 本发明涉及新的喹喔啉衍生物化合物，涉及包含所述化合物的药物组合物，制备所述化合物的方法以及所述化合物在治疗疾病中的用途， 癌症。
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3.发明公开SUBSTITUTED BENZOPYRAZIN DERIVATIVES AS FGFR KINASE INHIBITORS FOR THE TREATMENT OF CANCER DISEASES 有权代入为BENZOPYRAZINDERIVATE FGFR激酶抑制剂用于癌症治疗
公开(公告)号：EP2646432A1
公开(公告)日：2013-10-09
申请号：EP11805567.2
申请日：2011-11-29
发明人： BERDINI, Valerio , SAXTY, Gordon , MURRAY, Christopher William , BESONG, Gilbert Ebai , HAMLETT, Christopher Charles Frederick , WOODHEAD, Steven John , LIGNY, Yannick Aimé Eddy , ANGIBAUD, Patrick René
IPC分类号： C07D403/04 , A61K31/502 , A61P35/00
CPC分类号： C07D403/04 , C07D401/14 , C07D403/14
摘要： The invention relates to new quinoxaline derivative compounds of formula (I), to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
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公开(公告)号：EP2563775A1
公开(公告)日：2013-03-06
申请号：EP11724710.6
申请日：2011-04-28
发明人： SAXTY, Gordon , MURRAY, Christopher William , BERDINI, Valerio , BESONG, Gilbert Ebai , HAMLETT, Christopher Charles Frederick , JOHNSON, Christopher Norbert , WOODHEAD, Steven John , READER, Michael , REES, David Charles , MEVELLEC, Laurence Anne , ANGIBAUD, Patrick René , FREYNE, Eddy Jean Edgard , GOVAERTS, Tom Cornelis Hortense , WEERTS, Johan Erwin Edmond , PERERA, Timothy Pietro Suren , GILISSEN, Ronaldus Arnodus Hendrika Joseph , WROBLOWSKI, Berthold , LACRAMPE, Jean Fernand Armand , PAPANIKOS, Alexandra , QUEROLLE, Oliver Alexis Georges , PASQUIER, Elisabeth Thérèse Jeanne , PILATTE, Isabelle Noëlle Constance , BONNET, Pascal Ghislain André , EMBRECHTS, Werner Constant Johan , AKKARI, Rhalid , MEERPOEL, Lieven
IPC分类号： C07D403/04 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D487/08 , A61K31/498 , A61P35/00
CPC分类号： C07D403/04 , A61K31/498 , A61K31/5377 , A61K45/06 , C07D401/14 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D487/08 , C07D491/113 , C07F9/6524
摘要： The invention relates to new quinoxaline derivative compounds, to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
摘要翻译： 本发明涉及新的喹喔啉衍生物化合物，涉及包含所述化合物的药物组合物，制备所述化合物的方法以及所述化合物在治疗疾病中的用途， 癌症。
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公开(公告)号：EP3590934A1
公开(公告)日：2020-01-08
申请号：EP19175481.1
申请日：2011-04-28
发明人： SAXTY, Gordon , MURRAY, Christopher William , BERDINI, Valerio , BESONG, Gilbert Ebai , HAMLETT, Christopher Charles Frederick , JOHNSON, Christopher Norbert , WOODHEAD, Steven John , READER, Michael , REES, David Charles , MEVELLEC, Laurence Anne , ANGIBAUD, Patrick Rene , FREYNE, Eddy Jean Edgard , GOVAERTS, Tom Cornelis Hortense , WEERTS, Johan Erwin Edmond , PERERA, Timothy Pietro Suren , GILISSEN, Ronaldus Arnodus Hendrika Joseph , WROBLOWSKI, Berthold , LACRAMPE, Jean Fernand Armand , PAPANIKOS, Alexandra , QUEROLLE, Olivier Alexis Georges , PASQUIER, Elisabeth Therese Jeanne , PILATTE, Isabelle Noelle Constance , BONNET, Pascal Ghislain Andre , EMBRECHTS, Werner Constant Johan , AKKARI, Rhalid , MEERPOEL, Lieven
IPC分类号： C07D403/04 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D487/08 , A61K31/498 , A61P35/00
摘要： The invention relates to new quinoxaline derivative compounds, to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
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公开(公告)号：EP3178818B1
公开(公告)日：2019-05-22
申请号：EP16207610.3
申请日：2011-04-28
发明人： SAXTY, Gordon , MURRAY, Christopher William , BERDINI, Valerio , BESONG, Gilbert Ebai , HAMLETT, Christopher Charles Frederick , JOHNSON, Christopher Norbert , WOODHEAD, Steven John , READER, Michael , REES, David Charles , MEVELLEC, Laurence Anne , ANGIBAUD, Patrick René , FREYNE, Eddy Jean Edgard , GOVAERTS, Tom Cornelis Hortense , WEERTS, Johan Erwin Edmond , PERERA, Timothy Pietro Suren , GILISSEN, Ronaldus Arnodus Hendrika Joseph , WROBLOWSKI, Berthold , LACRAMPE, Jean Fernand Armand , PAPANIKOS, Alexandra , QUEROLLE, Olivier Alexis Georges , PASQUIER, Elisabeth Thérèse Jeanne , PILATTE, Isabelle Noëlle Constance , BONNET, Pascal Ghislain André , EMBRECHTS, Werner Constant Johan , AKKARI, Rhalid , MEERPOEL, Lieven
IPC分类号： C07D403/04 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D487/08 , A61K31/498 , A61P35/00
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7.发明授权SUBSTITUTED BENZOPYRAZIN DERIVATIVES AS FGFR KINASE INHIBITORS FOR THE TREATMENT OF CANCER DISEASES 有权代入为BENZOPYRAZINDERIVATE FGFR激酶抑制剂用于癌症治疗
公开(公告)号：EP2646432B1
公开(公告)日：2015-04-08
申请号：EP11805567.2
申请日：2011-11-29
发明人： BERDINI, Valerio , SAXTY, Gordon , MURRAY, Christopher William , BESONG, Gilbert Ebai , HAMLETT, Christopher Charles Frederick , WOODHEAD, Steven John , LIGNY, Yannick Aimé Eddy , ANGIBAUD, Patrick René
IPC分类号： C07D403/04 , A61K31/502 , A61P35/00
CPC分类号： C07D403/04 , C07D401/14 , C07D403/14
摘要： The invention relates to new quinoxaline derivative compounds of formula (I), to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
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