专利检索 ap:("AstraZeneca AB") AND inv:"ANDREWS, David, Michael" 第 1 页

1.

发明公开
2-ANILINOPURIN-8-ONES AS INHIBITORS OF TTK/MPS1 FOR THE TREATMENT OF PROLIFERATIVE DISORDERS 审中-公开
标题翻译： 2- ANILINOPURIN -8-酮AS TTK / MPS1用于治疗增殖性疾病的抑制剂

公开(公告)号：EP2212326A1

公开(公告)日：2010-08-04

申请号：EP08788695.8

申请日：2008-08-20

申请人： AstraZeneca AB

发明人： ANDREWS, David, Michael , JONES, Clifford, David , SIMPSON, Iain , WARD, Richard, Andrew

IPC分类号： C07D487/04 , A61K31/52 , A61P35/00

CPC分类号： C07D487/04

摘要： The invention relates to chemical compounds of the formula (I), or a pharmaceutically acceptable salt thereof, which possess inhibitory activity against the spindle checkpoint kinase: Tyrosine Threonine Kinase (TTK)/monopolar spindle 1 (Mpsl) and are accordingly useful for their anti-cancer effect in a warm-blooded animal such as man. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them, and to their use in the manufacture of a medicament for the treatment of conditions mediated by TTK/Mpsl, for use either alone or in combination with other anti-pro liferative agents.

2.

发明授权
BENZAMIDE COMPOUNDS USEFUL AS HISTONE DEACETYLASE INHIBITORS 有权
标题翻译： AS APPROPRIATE组蛋白去乙酰化酶抑制剂苯甲酰胺

公开(公告)号：EP1954690B1

公开(公告)日：2013-05-15

申请号：EP06794783.8

申请日：2006-10-17

申请人： AstraZeneca AB

发明人： ANDREWS, David, Michael , STOKES, Elaine Sophie Elizabeth , TURNER, Andrew , WARING, Michael, James

IPC分类号： C07D401/06 , A61P35/00 , A61K31/454

CPC分类号： C07D401/06